Registration Dossier
Registration Dossier
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EC number: 237-158-7 | CAS number: 13674-84-5
Endpoint summary
Administrative data
Description of key information
Skin irritation: Method:equivalent to OECD TG 404. Result:not irritating to skin.
Eye irritation: Method:equivalent to OECD TG 405. Result: not irritating to eye.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
There are a key study focused on investigating skin irritation and one study on eye irritation due to their high adequate which were performed according to OECD test guidelines and complying with GLP. They all showed that the test material was not irritating to skin and eye in rabbit. Therefore the TCPP was not irritating to skin and eye in rabbit.
Justification for classification or non-classification
No human data are available, however, there is an extensive database in animals, indicating that TCPP is non-irritant in the rabbit eye and skin. The lack of any substantial skin or eye irritation and the lack of irritation observed in the acute inhalation studies suggest that TCPP would be unlikely to produce significant respiratory tract irritation.
According to Annex 6 (Directive 67 /548 /EEC), no classification is proposed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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