Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 906-125-5 | CAS number: -
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable documented publication which meets basic scientific principles
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 979
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- Motoyoshi K et al.
- Year:
- 2 008
- Bibliographic source:
- RIFM Database
Materials and methods
- Endpoint addressed:
- skin irritation / corrosion
Test material
- Reference substance name:
- Geraniol
- EC Number:
- 203-377-1
- EC Name:
- Geraniol
- Cas Number:
- 106-24-1
- Molecular formula:
- C10H18O
- IUPAC Name:
- (2E)-3,7-dimethylocta-2,6-dien-1-ol
- Details on test material:
- - Name of test material (as cited in study report): Geraniol
- Analytical purity: > 95 %
Constituent 1
Method
- Details on study design:
- - Using a glass tuberculin syringe, 0.05 g of the test compound was transferred to the 15 mm patches which was then applied to the back of each subject for 48 hours.
- Patches were removed and sites swabbed with dry gauze to remove residual test material.
- Reactions were read 30 minutes after patch removal and if necessary at 72, 96, and 120 hours after patch removal
- Vehicle: acetone
- Concentration: 32%
Results and discussion
- Results:
- Geraniol was severe irritating (Score 3) at 32% in acetone
Applicant's summary and conclusion
- Conclusions:
- severe irritating
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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