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EC number: 230-949-8 | CAS number: 7381-01-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06-12-1993 to 03-01-1994
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Guideline study, summarily described, No GLP, no CoA i.e. no data on impurities, but biodeg monitored based on DOC data. Result sufficient as supporting study. Read-across is based upon a commonality of functional groups, constituents, breakdown products and metabolic pathways. A detailed justification is appended in Section 13.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- Deviations:
- yes
- Remarks:
- Number of replicates of test substance and reference substance is lower than required.
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum: activated sludge
Sample location: Sewage treatement plant Niederrad
number of viable micro-organisms: about 10^6 CFU
Pretreatment of inoculum: 1 day aerated befor use
Adaption : Not adapted to test substance
die Referenzsubstanz adaptiert - Duration of test (contact time):
- 28 d
- Initial conc.:
- 30 mg/L
- Based on:
- test mat.
- Initial conc.:
- 13.85 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- Test incubation at 20 ± 2 °C.
Test media according to OECD 301 E.
Sodium benzoate is used as reference substance and control without test substance is included
Test vessels: 1 L glas roundflasks covered with aluminium foil.
Test was performed without aeration.
Test was performed in the dark on a shaker. - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (DOC removal)
- Value:
- 94.1
- Sampling time:
- 28 d
- Details on results:
- No inhibition control was included in the test but based on the degradation of the test substance no inhibition of degradation was observed.
- Results with reference substance:
- OK
- Validity criteria fulfilled:
- yes
- Remarks:
- endogenous respiration acceptable, reference test result OK
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Despite the very limited description the test result is considered valid with an acceptable reliability
- Executive summary:
The ready biodegradability of sodium cocoyl isethionate has been demonstrated in an OECD 301E test. The test is considered valid but relatively summarily described. Not performed under GLP conditions and details on the quality of the test substance is missing. The result can be used as supporting study.
Reference
Time | Control | Sodium benzoate | Sodium Cocoyl Isethionate | ||
days | DOC (mg/L) | DOC (mg/L) | % degraded | DOC (mg/L) | % degraded |
0 | 0.3/0.3 | 20.3 | - | 13.85 | - |
7 | 0.3/0.3 | 2.0 | 91.5 | 1.15 | 93.7 |
14 | 0.3/0.3 | 1.2 | 95.5 | 1.10 | 94.1 |
21 | 0.3/0.3 | 0.8 | 97.5 | 1.60 | 90.4 |
28 | 0.3/0.3 | 0.8 | 97.5 | 1.10 | 94.1 |
Description of key information
Based upon read-across to Coco fatty acids 2-sulfoethyl ester, sodium salt, the lauric acid 2-sulfoethyl ester, sodium salt is considered to be readily biodegradable. Coco fatty acids 2-sulfoethyl ester, sodium salt is a UVCB substance and therefore was the 10-day windows not evaluated. No toxicity to the inoculum was observed at 1.62 mg a.i./L
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
There is no biodegradation screening test available for lauric acid 2-sulfoethyl ester, sodium salt (sodium lauroyl isethionate) CAS No 7381-01-3. There is however a study on the source chemical Coco fatty acids 2 -sulfoethyl ester, sodium salt CAS no 61789 -32 -0, which is rated Klimisch 2 and was carried out according to the OECD guideline 301E, as described in Bueckling and Pleschke, 1994.
The ready biodegradability of the test substance was determined in three different tests. Coco fatty acids 2 -sulfoethyl ester, sodium salt was found to be readily biodegradable in all three tests. In the key study by Buecking and Pleschke , a Closed Bottle test according to the slightly modified OECD, EEC and ISO test guidelines under GLP conditions is described and 94.1% degradation was observed at 14 and 28 days. No toxicity to the inoculum was observed. Read-across from the source chemical,Coco fatty acids 2 -sulfoethyl ester, sodium salt CAS no 61789 -32 -0 to the target chemical is considered to be justified based upon a commonality of functional groups, constituents, breakdown products and metabolic pathways.Therefore we consider these study endpoint results as sufficiently conservative to be taken account of in the risk assessment of lauric acid 2-sulfoethyl ester, sodium salt (sodium lauroyl isethionate) CAS No 7381-01-3.
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