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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Developmental toxicity / teratogenicity

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Administrative data

Endpoint:
developmental toxicity
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2010
Bibliographic source:
Toxicity Estimation Software Tool (T.E.S.T) v3.2, US EPA

Materials and methods

Test guideline
Guideline:
other: QSAR
Principles of method if other than guideline:
Developmental toxicity estimation by QSAR
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzene-1,2,4,5-tetracarboxylic acid
EC Number:
201-879-5
EC Name:
Benzene-1,2,4,5-tetracarboxylic acid
Cas Number:
89-05-4
Molecular formula:
C10H6O8
IUPAC Name:
benzene-1,2,4,5-tetracarboxylic acid

Results and discussion

Results: maternal animals

Effect levels (maternal animals)

Dose descriptor:
other: developmental toxicant value
Effect level:
0.21 other: absolute value
Based on:
act. ingr.
Basis for effect level:
other: developmental toxicity

Results (fetuses)

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
Substance is NOT a potential developmental toxicant