Registration Dossier
Registration Dossier
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EC number: 224-929-8 | CAS number: 4559-86-8
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
1,1,3,3-tetrabutylurea was tested in vitro and in vivo:
Bacterial Reverse Mutation Assays according to OECD Guideline 471 and EC directive 92/69/EEC, L 383 A: part B: Methods for the Determination of Toxicity - Mutagenicity (Escherichia coli WP2 uvr A - reverse mutation assay) with the strains S. typhimurium TA 1535, TA 1537, TA 1538, TA 98 and TA 100 and with E. coli WP2 uvr A
Mammalian Erythrocyte Micronucleus Test with rats according to OECD Guideline 474.
In all tests negative results have been obtained.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
As 1,1,3,3-tetrabutylurea was tested negative in vitro and also in vivo, there is no need for classification and labelling.
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