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EC number: 287-820-4 | CAS number: 85586-18-1
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 8th July 2010 - 8th August 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study was conducted in accordance with international guidelines in a GLP testing laboratory.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 13 Pa
- Remarks on result:
- other: The test item did not change in appearance under the conditions used in the determination.
- Transition / decomposition:
- no
- Conclusions:
- The vapour pressure of the test item has been determined to be 13 Pa at 25oC.
- Executive summary:
The vapour pressure of the test substance (PR-4758) was measured by the effusion vapour pressure balance method in accordance with international guidelines in a GLP testing laboratory, and the value was determined to be 13 Pa at 25 deg C.
Reference
Run 1
| Temperature (oC) |
Temperature (K) | Reciprocal Temperature (K-1) | Mass Difference (µg) | Mass Difference (kg) | Vapour Pressure (Pa) | Log10Vp |
| -19 | 254.15 | 0.003934684 | 133.41 | 1.334E-07 | 0.185207259 | -0.732341995 |
| -18 | 255.15 | 0.003919263 | 143.06 | 1.431E-07 | 0.198603932 | -0.702012158 |
| -17 | 256.15 | 0.003903963 | 158.77 | 1.588E-07 | 0.220413437 | -0.656761934 |
| -16 | 257.15 | 0.003888781 | 179.58 | 1.796E-07 | 0.249303048 | -0.603272412 |
| -15 | 258.15 | 0.003873717 | 198.26 | 1.983E-07 | 0.275235674 | -0.560295277 |
| -14 | 259.15 | 0.003858769 | 224.08 | 2.241E-07 | 0.311080449 | -0.507127283 |
| -13 | 260.15 | 0.003843936 | 255.44 | 2.554E-07 | 0.354616163 | -0.450241473 |
| -12 | 261.15 | 0.003829217 | 280.36 | 2.804E-07 | 0.389211508 | -0.409814327 |
| -11 | 262.15 | 0.003814610 | 317.01 | 3.170E-07 | 0.440091098 | -0.356457417 |
| -10 | 263.15 | 0.003800114 | 351.46 | 3.515E-07 | 0.487916524 | -0.311654474 |
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 1 gives the following statistaical data using an unweighted least squares treatment.
Slope: -3222.445
Std. dev. in slope: 57.032
Intercept: 11.931
Std. dev. in intercept: 0.221
The results obtained indicate the following vapour pressure relationship:
Log10 (Vp (Pa))=-3222.445/temp(K) + 11.931
The above yields a vapour pressure (Pa) at 298.15K with a common logarithm of 1.123
Run 2
| Temperature (oC) |
Temperature (K) | Reciprocal Temperature (K-1) | Mass Difference (µg) | Mass Difference (kg) | Vapour Pressure (Pa) | Log10Vp |
| -19 | 254.15 | 0.003934684 | 125.95 | 1.260E-07 | 0.174850868 | -0.757332207 |
| -18 | 255.15 | 0.003919263 | 135.84 | 1.358E-07 | 0.188580722 | -0.724502706 |
| -17 | 256.15 | 0.003903963 | 150.67 | 1.507E-07 | 0.209168561 | -0.679503590 |
| -16 | 257.15 | 0.003888781 | 167.50 | 1.675E-07 | 0.232532913 | -0.633515567 |
| -15 | 258.15 | 0.003873717 | 191.64 | 1.916E-07 | 0.266045418 | -0.575044217 |
| -14 | 259.15 | 0.003858769 | 215.18 | 2.152E-07 | 0.298724969 | -0.524728476 |
| -13 | 260.15 | 0.003843936 | 239.60 | 2.396E-07 | 0.332626185 | -0.478043565 |
| -12 | 261.15 | 0.003829217 | 266.13 | 2.661E-07 | 0.369456622 | -0.432436545 |
| -11 | 262.15 | 0.003814610 | 301.56 | 3.016E-07 | 0.418642539 | -0.378156644 |
| -10 | 263.15 | 0.003800114 | 336.75 | 3.368E-07 | 0.467495275 | -0.330222774 |
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 2 gives the following statistaical data using an unweighted least squares treatment.
Slope: -3250.177
Std. dev. in slope: 54.313
Intercept: 12.016
Std. dev. in intercept: 0.210
The results obtained indicate the following vapour pressure relationship:
Log10 (Vp (Pa))=-3250.177/temp(K) + 12.016
The above yields a vapour pressure (Pa) at 298.15K with a common logarithm of 1.115
Run 3
| Temperature (oC) |
Temperature (K) | Reciprocal Temperature (K-1) | Mass Difference (µg) | Mass Difference (kg) | Vapour Pressure (Pa) | Log10Vp |
| -19 | 254.15 | 0.003934684 | 122.63 | 1.226E-07 | 0.170241858 | -0.768933650 |
| -18 | 255.15 | 0.003919263 | 134.63 | 1.346E-07 | 0.186900932 | -0.728388533 |
| -17 | 256.15 | 0.003903963 | 147.16 | 1.472E-07 | 0.204295782 | -0.689740600 |
| -16 | 257.15 | 0.003888781 | 159.00 | 1.590E-07 | 0.220732736 | -0.656133254 |
| -15 | 258.15 | 0.003873717 | 181.81 | 1.818E-07 | 0.252398859 | -0.597912612 |
| -14 | 259.15 | 0.003858769 | 211.38 | 2.114E-07 | 0.293449595 | -0.532466485 |
| -13 | 260.15 | 0.003843936 | 230.80 | 2.308E-07 | 0.320409531 | -0.494294574 |
| -12 | 261.15 | 0.003829217 | 262.49 | 2.625E-07 | 0.364403370 | -0.438417616 |
| -11 | 262.15 | 0.003814610 | 298.12 | 2.981E-07 | 0.413866938 | -0.383139266 |
| -10 | 263.15 | 0.003800114 | 330.70 | 3.307E-07 | 0.459096325 | -0.338096184 |
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 3 gives the following statistaical data using an unweighted least squares treatment.
Slope: -3282.406
Std. dev. in slope: 86.818
Intercept: 12.129
Std. dev. in intercept: 0.336
The results obtained indicate the following vapour pressure relationship:
Log10 (Vp (Pa))=-3282.406/temp(K) + 12.129
The above yields a vapour pressure (Pa) at 298.15K with a common logarithm of 1.120
Run 4
| Temperature (oC) |
Temperature (K) | Reciprocal Temperature (K-1) | Mass Difference (µg) | Mass Difference (kg) | Vapour Pressure (Pa) | Log10Vp |
| -19 | 254.15 | 0.003934684 | 117.94 | 1.179E-07 | 0.163730936 | -0.785869255 |
| -18 | 255.15 | 0.003919263 | 134.08 | 1.341E-07 | 0.186137391 | -0.730166377 |
| -17 | 256.15 | 0.003903963 | 146.13 | 1.461E-07 | 0.202865878 | -0.692790994 |
| -16 | 257.15 | 0.003888781 | 162.52 | 1.625E-07 | 0.225619397 | -0.646623565 |
| -15 | 258.15 | 0.003873717 | 177.00 | 1.770E-07 | 0.245721347 | -0.609557112 |
| -14 | 259.15 | 0.003858769 | 200.33 | 2.003E-07 | 0.278109364 | -0.555784388 |
| -13 | 260.15 | 0.003843936 | 229.96 | 2.300E-07 | 0.319243395 | -0.495878079 |
| -12 | 261.15 | 0.003829217 | 256.88 | 2.569E-07 | 0.356615252 | -0.447800086 |
| -11 | 262.15 | 0.003814610 | 287.72 | 2.877E-07 | 0.399429073 | -0.398560327 |
| -10 | 263.15 | 0.003800114 | 325.33 | 3.253E-07 | 0.451641389 | -0.345206266 |
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 4 gives the following statistaical data using an unweighted least squares treatment.
Slope: -3248.810
Std. dev. in slope: 66.317
Intercept: 11.991
Std. dev. in intercept: 0.256
The results obtained indicate the following vapour pressure relationship:
Log10 (Vp (Pa))=-3248.810/temp(K) + 11.991
The above yields a vapour pressure (Pa) at 298.15K with a common logarithm of 1.095
Summary
| Run | Log10[Vp(25oC)] |
| 1 | 1.123 |
| 2 | 1.115 |
| 3 | 1.120 |
| 4 | 1.095 |
| Mean | 1.113 |
| Vapour Pressure | 13 Pa |
Description of key information
Vapour pressure = 13 Pa at 25°C, EU Method A4; SP Tremain & SS Atwal (2013)
Key value for chemical safety assessment
- Vapour pressure:
- 13 Pa
- at the temperature of:
- 25 °C
Additional information
A single key study was used to determine the vapour pressure of PR-4758. The study was conducted in accordance with EU guidelines and in accordance with GLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
