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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
respiratory sensitisation: in vivo
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 1951-97-9
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-DK-EPA

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Respiratory allergy. Multicase model
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
Piperazine compound with phosphoric acid
IUPAC Name:
Piperazine compound with phosphoric acid
Constituent 2
Chemical structure
Reference substance name:
Piperazine, compound with phosphoric acid
EC Number:
217-775-8
EC Name:
Piperazine, compound with phosphoric acid
Cas Number:
1951-97-9
Molecular formula:
C4H10N2.xH3O4P
IUPAC Name:
phosphoric acid; piperazine
Details on test material:
-Name of the test material : Piperazine compound with phosphoric acid
-Substance type : Organic
-Physical state : Solid

Test animals

Species:
other: no data
Strain:
not specified
Sex:
not specified

Test system

Route of induction exposure:
other: no data
Route of challenge exposure:
other: no data
Vehicle:
not specified

Results and discussion

Results:
The substance piperazine compound with phosphoric acid gave positive result for respiratory sensitisation.

Applicant's summary and conclusion

Interpretation of results:
sensitising
Conclusions:
The substance piperazine compound with phosphoric acid gave positive result for respiratory sensitisation.
Executive summary:

The substance piperazine compound with phosphoric acid gave positive result for respiratory sensitisation.