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EC number: 203-336-8 | CAS number: 105-83-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Aquatic toxicity
Based on the available data, it can be concluded that the substance is acutely harmful to aquatic organisms.
Short-term toxicity to fish
The toxicity of N,N-bis(3 -aminopropyl)methylamine (CAS 105 -83 -9) was studied in a static test according to national standards (DIN 38412, part 15). The test item concentrations were not analytically verified, but are assumed to be stable regarding the low volatility. The 96 -h LC50 was determined to be 147 mg/L. In addition to the not pH-adjusted test solutions, the highest test concentration of 1000 mg/L was tested in parallel after neutralisation. This treatment had no effect on the fish, while all fish were dead after 1 h at 1000 mg/L when the pH was not adjusted (BASF AG, 1987; report no. 87/189).
In conclusion, the test substance is with high probability acutely not harmful to fish.
Long-term toxicity to fish
No data available.
Short-term toxicity to aquatic invertebrates
The acute toxicity of N,N-bis(3 -aminopropyl)methylamine (CAS 105 -83 -9) was studied in a static test according to method OECD 202. The test item concentrations were analytically verified and were stable during the exposure period (±20% of nominal). Therefore the effect concentrations are based on the nominal values. The 48-h EC50 was determined to be 18.1 mg/L (BASF SE, 2012; report no. 50E0435/11E097).
In conclusion, the substance is acutely harmful to aquatic invertebrates.
Long-term toxicity to aquatic invertebrates
No data available
Toxicity to aquatic algae and cyanobacteria
There is one reliable study available regarding the toxic effect of N,N-bis(3 -aminopropyl)methylamine (CAS 105 -83 -9). The study was performed according to OECD 201 under GLP conditions. The test species was Desmodesmus subspicatus. The test concentrations were analytically verified. The measured concentrations were ±20% of the nominal values (97% to 111% mean recovery) with an exception of the lowest test concentration (1 mg/L, nominal), which had a recovery at test start of 200% and was below the LOQ at test end. Nevertheless the effect values are based on nominal concentrations since the lowest concentrations did not show any negative effects. The 72 -h effect values are as follows: NOErC = 3.2 mg/L, ErC10 = 12.6 mg/L, ErC50 62.6 mg/L (BASF SE, 2012; report no. 60E0435/11E098).
In conclusion, the substance is acutely harmful to algae.
Toxicity to microorganisms
The microbial toxicity of N,N-bis(3 -aminopropyl)methylamine (CAS 105 -83 -9) was studied in a non-GLP guideline study according to ISO 8192 (respiration inhibition test with activated sludge) . The respiration inhibition test used activated sludge as inoculum taken from a wwtp treating predominantly domestic sewage. The 3 -h EC20 was determined to be greater than 1000 mg/L (BASF AG, 1990; report no. 01.89/2040).
In conclusion, the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
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