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EC number: 235-697-2 | CAS number: 12542-30-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Hexahydro-4,7-methano-1H-indenyl acrylate
- EC Number:
- 235-697-2
- EC Name:
- Hexahydro-4,7-methano-1H-indenyl acrylate
- Cas Number:
- 12542-30-2
- Molecular formula:
- C13 H16 O2
- IUPAC Name:
- 2-Propenoic acid hexahydro-4,7-methano-1H-indenyl ester
- Details on test material:
- - Name of test material (as cited in study report): Dihydrodicyclopentadienylacrylate
- Physical state: liquid/colorless, clear
- Analytical purity: 97.7 corr. area-% as a sum of four single peaks with a molecular mass of 204. The main peak of these four peaks has 91.3 corr. area-%
- Lot/batch No.: 110019P040
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- -Test species and strain: Pseudokirchneriella subcapitata KORSHIKOV (SAG 61.81)
-Age: A stock algal culture is maintained continuously at the test facility. Before the exposure an inoculum culture is prepared from the stock culture and incubated for 4 days at 21 – 24 °C (max. temperature difference 2 °C). After this time, the inoculum culture is in exponential growth phase and can be used to initiate the test (study day 0).
-Supplier: Collection of algal cultures in University of Göttingen /Germany
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
Test conditions
- Test temperature:
- 23.2 - 23.5 °C
- Nominal and measured concentrations:
- 0 (control), 0.32, 1.0, 3.2, 10 and 32 mg/L as nominal concentrations based on technical test substance mass without correction for purity
0 (control), 0.23, 0.78, 2.60, 8.26 and 26.6 mg/L as geometric mean measured concentrations based on technical test substance mass without correction for purity - Details on test conditions:
- TEST SYSTEM
- Test vessel: Erlenmeyer flasks (nominal volume 250 mL) closed with glass plugs Glass flask closed with glass plugs (nominal volume 50mL); for additional uninoculated replicates 8 & 9 only.
- Type (delete if not applicable): closed
- Initial cells density: 0.3 x 104 cells/mL
- No. of vessels per concentration (replicates): 3
- No. of vessels per control (replicates):6
GROWTH MEDIUM
- Standard medium used: yes
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod:
- Light intensity and quality: Average 4798 lux (within ± 15% variability) at a wave length of 400 - 700 nm
TEST SUBSTANCE PREPARATION
-The stock solution (35.5 mg/L) was prepared by pipetting test substance (165 µL based on the density) into 5L of test medium and stirring for about one day in a sealed flask. The test solutions were prepared at 111% of the nominal concentration to compensate for the dilution by the later addition of algal inoculum. The test concentrations were prepared from a dilution of a stock solution.
The dissolution of the test substance in water is slow. Therefore the stock solution was stirred for about one day. to ensure that the test substance was completely dissolved.
All test solutions were visibly clear following preparation. - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 2.99
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- 1.58 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Any other information on results incl. tables
Algal Yield [mg/L] |
Algal Growth Rate [mg/L] |
||
EyC10 confidence limits 95%: |
0.21 0.18 – 0.24 |
ErC10 confidence limits 95%: |
1.58 1.17 – 2.14 |
EyC20 confidence limits 95%: |
0.32 0.29 – 0.36 |
ErC20 confidence limits 95%: |
1.97 1.63 – 2.38 |
EyC50 confidence limits 95%: |
0.75 0.70 – 0.80 |
ErC50 confidence limits 95%: |
2.99 2.68 – 3.34 |
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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