Registration Dossier
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Diss Factsheets
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EC number: 216-378-7 | CAS number: 1569-69-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Persistence
Cyclohexylmercaptan was not readily biodegradable (0% degradation in 28 days) in a standard test conducted according to OECD 301F (Youngs, 2009); no other biodegradation data are available. It does not contain any functional groups that are susceptible to hydrolysis and no data are available on other abiotic degradation mechanisms. The substance therefore meets the screening criteria for persistence (P or vP) according to REACH Technical Guidance Chapter R.11.
Bioaccumulation
Cyclohexylmercaptan has a measured log log Kow of 3.7, determined in a study conducted according to OECD 117 (Baltussen, 2013). No measured bioaccumulation data are available. The substance does not meet the screening criteria for B or vB according to REACH Technical Guidance Chapter R.11.
Toxicity
Acute aquatic toxicity data are available for invertebrates and algae. The lowest measured EC50 is 0.43 mg/l for algae, determined in a test conducted according to OECD 202 (Harlan Laboratories Ltd, 2009b). The 72-hour NOEC in this study was 0.15 mg/l. No other chronic ecotoxicity data are available. On the basis of the available measured data, cyclohexylmercaptan does not meet the screening criteria for toxicity (T) for the environment, according to REACH Technical Guidance Chapter R.11.
Based on the limited dataset that is currently available, cyclohexylmercaptan is not classified for carcinogenicity, mutagenicity, reproductive toxicity or specific target organ toxicity following repeated exposures. Additional toxicological testing is not warranted for this substance based on the relevant REACH Annex requirements. On the basis of the available information the substance does not meet the criteria for toxicity for mammalian effects according to REACH Technical Guidance Chapter R.11.
Overall conclusions
Cyclohexylmercaptan may be persistent in the environment but it is not bioaccumulative or toxic according to the criteria set out in REACH Technical Guidance Chapter R.11. It is therefore not considered to be PBT or vPvB.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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