Registration Dossier
Registration Dossier
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EC number: 233-786-0 | CAS number: 10361-29-2
Repeated dose toxicity: oral
Administrative data
- Endpoint:
- repeated dose toxicity: oral
- Remarks:
- other: read -across from 90 days study an analogue
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The analogue shares the same finctional group with Ammmonium carbonate.
Data source
Reference
- Reference Type:
- other: read-across
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
- Principles of method if other than guideline:
- Read across on analogue substance.
- GLP compliance:
- no
Test material
- Reference substance name:
- Ammonium chloride
- EC Number:
- 235-186-4
- EC Name:
- Ammonium chloride
- Cas Number:
- 12125-02-9
- IUPAC Name:
- ammonium chloride
Constituent 1
Results and discussion
Effect levels
- Dose descriptor:
- NOAEL
- Effect level:
- 1 256 mg/kg bw/day (nominal)
- Based on:
- test mat.
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
- Conclusions:
- NOAEL (90days)=1256mg/kg bw.
- Executive summary:
NOAEL (90days)=1256mg/kg bw.
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