Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 269-505-3 | CAS number: 68259-02-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
A GLP-compliant study was performed to measure the abiotic degradation of the read across test article according to OECD guideline 111 at 50 ± 0.1 °C at each of pH 4.0, pH 7.0, and pH 9.0. The results of pH 7.0 and pH 9.0 showed no significant degradation of FAT 45168/A. The percentage of the hydrolysis at pH 7.0 and pH 9.0 respectively was found to be less than 10 % after 5 days incubation at 50 °C ± 0.1 °C. In conclusion, FAT 45168/A was considered to be hydrolytically stable at pH 7.0 and pH 9.0. Therefore, according to the guidelines no further testing of FAT 45'168/A was performed at pH 7.0 and pH 9.0. The results at pH 4.0 showed that FAT 45168/A is not stable at this pH range. The percentage of hydrolysis at pH 4.0 was found to be more than 10 % after 5 days. Therefore, according to the guidelines advanced testing of FAT 45168/A was performed to determine the rate constant (K25) of the FAT 45168/A hydrolysis reaction at pH 4.0. As a result of all observations, it can be stated that the hydrolysis reaction of FAT 45168/A at pH 4.0 and 25 °C was estimated to be relative slow (t1/2 (25 °C) = about 100 days). The activation energy of FAT 45168/A at pH4.0 was estimated to be 60.1 kJ/mol and the reaction rate constant (K) of FAT 45168/A at pH 4.0 was estimated to be 2.9 10E-4 per hour.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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