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EC number: 202-090-9 | CAS number: 91-68-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Appearance/physical state/colour :
On the basis of physical observation and using the sense of smell 3-diethylaminophenol was found to be an organic solid, with black colour and characteristic odour.
Melting point/freezing point :
The melting point of 3-diethylaminophenol by the capillary method was found to be 49 deg C at an atmospheric pressure of 955 hPa. There was no decomposition & sublimation observed of 3-diethylaminophenol at the melting point. This value when converted to 101325 Pa is equivalent to 51.98 deg C. The supporting studies shows value in the range of 72 -78 deg C which could be due to difference in the estimation condition. However for the purpose of chemical safety assessment Key stydy value 51.98 deg C shall be considered
Boiling point :
The boiling point of 3-diethylaminophenol by the distillation method was found to be 440 degC at the atmospheric pressure of 955 hPa. No decomposition of 3-diethylaminophenol was observed at the boiling point.This value when converted to 101325 Pa is equivalent to 466.83 deg C. The supporting studies shows value in the range of 265-280 deg C which could be due to difference in the estimation condition. Therefore for the purpose of chemical safety assessment key study value 466.83 deg C shall be considered.
Density :
The bulk density of 3-diethylaminophenol by the mass by volume method was found to be 1.04g/cm3 at room temperature of 23 °C .This value when converted to 20 deg C is equivalent to 0.9043g/cm3.
Particle size distribution (Granulometry) :
The particle size distribution (granulometry) of 3-diethylaminophenol by the sieve analysis method was not possible as the substance is rock solid and so particle size distribution was not possible.
Vapour pressure :
According to EPI (Estimation Programs Interface) Suite vapour pressure of 3-diethylaminophenol at 25 degC is estimated as 0.000809 mm Hg by means of Modified Grain Method
Partition coefficient :
The experimental value of octanol water partition co-efficient (log Pow) of 3-diethylaminophenol by Shake flask method was found to be 0.9294 at temperature 23 degC and pH of 7.3.This value indicates that 3-diethylaminophenol is hydrophilic in nature.
Water solubility :
The experimental value of the water solubility of 3-diethylaminophenol was found to be 1500 mg/L at temperature of 23degC indicating that 3-diethylaminophenol is soluble in water.The supporting study shows value different from key studies which could be due to difference in estimation conditions.
Solubility in organic solvents / fat solubility :
The experimental value of solubility of 3-diethylaminophenol in methanol at temperature of 23 degC was found to be 4700mg/L indicating that 3-diethylaminophenol is soluble in methanol.This value at 20 deg C is equivalent to 4086.95 mg/L. The solubility of 3-diethylaminophenol in Petroleum ether at temperature of 23 degC was found to be 2400mg/L indicating that 3-diethylaminophenol is soluble in Petroleum ether.
Surface tension :
In accordance with Column 2 adaptation statement of REACH Annex VII, information requirement 7.6, this end point was considered for waiver since surface activity was not a desired property of 3-diethylaminophenol.
Flash point :
The experimental value of flash point for 3-diethylaminophenol by the open cup method was found to be 109 deg C at 955 hPa atmospheric pressure. This value when converted to 101325 Pa is equivalent to 115.64 deg C.
Auto flammability :
3-diethylaminophenol did not catch fire on being exposed to air at room temperature of 23 deg C and atmospheric pressure of 955 hPa. This indicates that 3-diethylaminophenol is not auto-flammable.
Flammability :
From the experimental values of flammability,3-diethylaminophenolignited when the flame of bunsen burner having temperature of 950 degC was brought in contact with it. Thus it can be concluded that3-diethylaminophenolis flammable only at high temperature of about 950 degC. However since such high temperatures are not found under normal circumstances of transportation and use,3-diethylaminophenol was considered non-flammable.
Explosiveness :
According to theoretical considerations based on chemical structure, 3-diethylaminophenol does not possess explosive properties. The reason for this is there are no chemical groups associated with explosive properties in 3-diethylaminophenol. Thus, as per column 2 of Annex VII this end point was considered for waiver.
Oxidising properties :
3-diethylaminophenolwas found to be non - oxidising since 6051 ml of KMnO4 was required for getting the end point of the redox titration for 100 g of 3-diethylaminophenol.
Stability in organic solvents and identity of relevant degradation products :
3-diethylaminophenol was found to be stable in organic solvent dichloro methane and no degradation products were formed after 24 hours as evident from the GC-MS chromatogram obtained at 0 hours and that obtained after 24 hours.
pH :
1% by volume solution of 3-diethylaminophenolwas found to exhibit a pH of 8.11 at 24 deg C. Thus 1% by volume solution of 3-diethylaminophenolis relatively basic in nature.
Dissociation constant :
The experimental pKa value for 3-diethylaminophenol was found to be 0.000000000000000995 (average pKa value) at 23 degC indicating that the chemical has dissociation properties. This value at 20 deg C is equivalent to 0.0000000000000008652174.
Viscosity :
This end point was considered for waiver since viscosity is an inherent property of a liquid that offers resistance to its flow and 3-diethylaminophenol is a solid substance and hence this testing was considered scientifically unjustified for 3-diethylaminophenol.
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