Registration Dossier
Registration Dossier
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EC number: 228-626-1 | CAS number: 6309-51-9
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Study period:
- 1987
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Basic data given
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 987
- Report date:
- 1987
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- Deviations:
- yes
- Remarks:
- only basic data given; lack of details on test substance; observation time not given
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Hexyl laurate
- EC Number:
- 251-932-1
- EC Name:
- Hexyl laurate
- Cas Number:
- 34316-64-8
- Molecular formula:
- C18H36O2
- IUPAC Name:
- hexyl laurate
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- NMRI
- Sex:
- male
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Weight at study initiation: 21 g
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- unchanged (no vehicle)
- Doses:
- 5 mL/kg bw
- No. of animals per sex per dose:
- 5
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 4 300 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: converted from 5 mL/kg bw based on a density of 0.87 g/mL, see IUCLID Section "Physical and chemical properties, Density"
- Mortality:
- No mortality occurred during the study period.
- Clinical signs:
- other: Significant absence of reactions.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- CLP: not classified
DSD: not classified
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