Registration Dossier
Registration Dossier
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EC number: 941-482-0 | CAS number: 1044764-08-0
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
Workers - Hazard for the eyes
Additional information - workers
No reliable dose descriptor could be set for acute toxicity. Therefore an acute toxicity DNEL has not been derived. The test substance showed to be only slightly toxic to rats after acute oral uptake. Due to the handling under strictly controlled conditions, and the low vapour pressure high peak exposures are not probable.
Based on the available data on skin and eye irritation, no sufficiently robust DNEL could be set.
In a weight of evidence approach the substance was classified as “corrosive to the skin” according to Directive 67/548/EEC and “Skin Corrosion Category 1A” according to GHS Regulation EC No 1272/2008. Based on the skin corrosivity the substance is classified as “corrosive to the eye” according to Directive 67/548/EEC and “Category 1 (Irreversible effects on the eye)” according to GHS Regulation EC No 1272/2008.
No DNEL for skin sensitization was established. According to Directive 67/548/EEC as well as GHS Regulation EC No 1272/2008 the test substance is classified as “sensitizing category 1”.
There are neither data from human experience nor from other sources indicating respiratory sensitization.
General Population - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard via oral route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard for the eyes
Additional information - General Population
Due to the use as an intermediate the general population will not be exposed to the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
