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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

A key study performed under OECD guideline 202 with GLP shows no toxicity on Daphnia magna and gives an EC50 (48h) > 999 mg/L and a NOEC (48h) of 999 mg/L Trifluoroacetic acid. 

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
999 mg/L

Additional information

This endpoint is covered by one key study (Groeneveld, 1992), performed according to OECD 202 guideline and GLP, which evaluated the acute toxicity of Sodium trifluoroacetate (NaTFA) on the water fleas Daphnia magna, for 48h.

All validity criteria were fulfilled, this study was reliable without restriction. The study is a limit test at 1200 mg/l of Trifluoroacetate sodium in triplicates (i.e. 999 mg/l of Trifluoroacetic acid, TFA) with control. The selection of the limit test was based on the results of a range finding test. No mortality was observed so the EC50 (48h) was determined as greater than 999 mg/l and the NOEC is equal to 999 mg/l of TFA.