Registration Dossier
Registration Dossier
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EC number: 226-971-2 | CAS number: 5580-58-5
Endpoint summary
Administrative data
Description of key information
Additional information
Within the category of ‘yellow disazo condensation pigments’ acute aquatic toxicity data on all three trophic levels are available. This includes two studies for acute toxicity on guppy Poecilia reticulata (CAS 5580-57-4 and CAS 68516-73-4), two studies on immobilization of the waterflea Daphnia magna (CAS 5580-57-4 and CAS 68516-73-4) and one study of toxicity on the green algae Desmodesmus subspicatus (CAS 5280-80-8).
Disazo condensation yellow pigments are all of low solubility in water and in octanol. They do not contain functional groups that are susceptible to pH dependent hydrolysis at environmentally relevant pH. The pigments are generally not readily biodegradable and additionally adsorption to the solid soil phase is not expected. Due to the low logPow and the high molecular weight of all pigments, bioaccumulation is not expected. Their all decompose before melting. Since the molecular structure and the physico-chemical properties of the ‘yellow disazo condensation pigments’ are very similar, the available studies are sufficient to cover the aquatic toxicity endpoints of the whole category. Therefore, this read across approach is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach as it is explained within the analogue justification in the Annex.
After exposure to ‘yellow disazo condensation pigments’, no effects on aquatic organisms occurred within the range of water solubility. These results confirm the expectation, that ‘yellow disazo condensation pigments’ are considered to be essentially not bioavailable, due to the large molecular size together with the negligible low solubility.
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