Registration Dossier
Registration Dossier
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EC number: 200-860-9 | CAS number: 75-31-0
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in mammalian cells
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- other: Safety Data Sheet
Data source
Reference
- Reference Type:
- publication
- Title:
- Sikkerhedsdatablad Isopropylamin, Oxea
- Author:
- Oxea
- Year:
- 2 011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 476 (In Vitro Mammalian Cell Gene Mutation Test)
Test material
- Reference substance name:
- Isopropylamine
- EC Number:
- 200-860-9
- EC Name:
- Isopropylamine
- Cas Number:
- 75-31-0
- Molecular formula:
- C3H9N
- IUPAC Name:
- propan-2-amine
Constituent 1
Results and discussion
Test results
- Species / strain:
- other: mouse lymphoma cells
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative with metabolic activation
negative without metabolic activation
The substance does not show mutagenicity to mouse lyphomea cells, eighter with or without metabolic activation.
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