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Diss Factsheets
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EC number: 905-983-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1989
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- ISO 8192 (Water quality - Test for inhibition of oxygen consumption by activated sludge for carbonaceous and ammonium oxidation)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- purity not specified
Molecular formula: C21H32O4
Molecular weight: 349 g/mol - Analytical monitoring:
- no
- Test organisms (species):
- activated sludge
- Details on inoculum:
- - Initial biomass concentration: 6.0 g/L (dry weight)
- laboratory scale sewage treatment plant treating synthetic sewage (OECD 209) - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
- Test temperature:
- 21.4°C
- pH:
- 7.9
- Dissolved oxygen:
- O2 - Start: 2.9 - 7.9 mg
O2 - End: 2.0 - 6.1 mg - Nominal and measured concentrations:
- nominal: 100, 1000 and 10000 mg/L
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorphenole
- Key result
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Details on results:
- The concentrations of the test item and reference compound were not confirmed by analytical methods, but instead based on nominal concentrations.
- Results with reference substance (positive control):
- EC50 of the reference compound 3.5-Dichlorophenol is < 20 mglL
- Validity criteria fulfilled:
- yes
- Remarks:
- on the basic of graphic evaluation; The EC50 for 3,5-DCP was < 20 mg/L and between the prescribed limits of 5 and 30 mg/L.
- Conclusions:
- A test with activated sludge with a duration fo 3 hours was performed according to the OECD Guideline 209 which is equivalent to ISO 8192 (Test for Inhibition of Oxygen Consumption by Activated Sludge). For 'Reaction mass of benzyl 2-ethylhexyl adipate and bis(2-ethylhexyl) adipate and dibenzyl adipate' an EC50 of > 10000 mg/L was observed.
- Executive summary:
A test with activated sludge with a duration for 3 hours was performed according to the OECD Guideline 209 which is equivalent to ISO 8192 (Test for Inhibition of Oxygen Consumption by Activated Sludge).
The purpose of this test was to provide a rapid screening method whereby substances which may adversely affect aerobic microbial treatment plants can be identified, and to indicate suitable non-inhibitory concentrations of test items to be used in biodegradability tests. The method assessed the effect of a test item on microorganisms by measuring the respiration rate under defined conditions in the presence of different concentrations of the test item. With 'Reaction mass of benzyl 2-ethylhexyl adipate and bis(2-ethylhexyl) adipate and dibenzyl adipate' no respiration inhibition was observed at 100, 1000 and 10000 mg/L. Therefore the EC50 is higher than 10000 mg/L.
Reference
Description of key information
A test with activated sludge with a duration fo 3 hours was performed. For 'Reaction mass of benzyl 2-ethylhexyl adipate and bis(2-ethylhexyl) adipate and dibenzyl adipate' an EC50 of > 10000 mg/L was observed.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 10 000 mg/L
Additional information
A test with activated sludge with a duration for 3 hours was performed according to the OECD Guideline 209 which is equivalent to ISO 8192 (Test for Inhibition of Oxygen Consumption by Activated Sludge).
The purpose of this test was to provide a rapid screening method whereby substances which may adversely affect aerobic microbial treatment plants can be identified, and to indicate suitable non-inhibitory concentrations of test items to be used in biodegradability tests. The method assessed the effect of a test item on microorganisms by measuring the respiration rate under defined conditions in the presence of different concentrations of the test item. With 'Reaction mass of benzyl 2-ethylhexyl adipate and bis(2-ethylhexyl) adipate and dibenzyl adipate' no respiration inhibition was observed at 100, 1000 and 10000 mg/L. Therefore the EC50 is higher than 10000 mg/L.
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