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Diss Factsheets
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EC number: 280-518-3 | CAS number: 83682-78-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28 days
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Guideline study to GLP, 2016
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- GLP compliance:
- yes
- Specific details on test material used for the study:
- COCAMIDOPROPYL PG - DIMONIUM CHLORIDE PHOSPHATELOT # 50113A16
Date Received: 07 Mar 16;
Physical Description: Clear liquid
Storage Conditions: Room temperature
Purity: 41% active ingredient - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 28 d
- Initial conc.:
- ca. 0.8 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- Two replicates removed on days 7, 14, 21 and 28, with controls removed day 0
Two replicates serving as blank controlTwo replicates service as positive control (aniline)Toxicity control was run until Day 14 to confirm activity taking place - Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- ca. 30
- Sampling time:
- 7 d
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- ca. 48
- Sampling time:
- 14 d
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- ca. 98
- Sampling time:
- 21 d
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- ca. 73
- Sampling time:
- 28 d
- Details on results:
- Two replicates were taken on each sampling time except the final day (Day 28) with the percentage biodegradation based on a meanThe Oxygen figures for Day 21 were 5.32 and 6.80 and within an expected range if following trends from Day 0 - Day 14The Day 28 Oxygen figures ranged from 5.22 - 6.73 (excluding outliers), but the mean of 9 bottles resulted in a calculated biodegradation of 73%Based on the Day 7 and Day 21 figures, > 60% biodegradation was apparent in the 14 Day window.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Based on the Day 7 and Day 21 figures, > 60% biodegradation was apparent in a 14 Day window. The substance is considered biodegradable, although the 10-day criteria was not possible to prove. The final conclusion is backed up by examination of other similar chemical substances.
- Executive summary:
Despite using a closed bottle test at low concentrations of test material, a good level of biodegradation was acheived with over 90% recorded on Day 21 (but mean measurements falling back to 73% by Day 28). The low number of sample points and low number of replicates means that it is not possible to make an accurate assessment of the 10 Day window needed for CLP Classification, but if a curve is fitted to the time points 0 - 21 Days, it is conisdered very likely that the 10 Day window was acheived.
Reference
Description of key information
Despite using a closed bottle test at low concentrations of test material, a good level of biodegradation was acheived with over 90% recorded on Day 21 (but mean measurements falling back to 73% by Day 28). The low number of sample points and low number of replicates means that it is not possible to make an accurate assessment of the 10 Day window needed for CLP Classification, but if a curve is fitted to the time points 0 - 21 Days, it is conisdered very likely that the 10 Day window was acheived.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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