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Diss Factsheets
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EC number: 280-518-3 | CAS number: 83682-78-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 96 hours
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Justification for type of information:
- Performed to guidelines, but no supporting analysis
The substance is supplied in water and is considered stable, - Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Tested as 7% actives product in water for supply
- Analytical monitoring:
- no
- Vehicle:
- yes
- Remarks:
- Water
- Test organisms (species):
- other: turbot
- Details on test organisms:
- Juvenile fish used
- Test type:
- static
- Water media type:
- saltwater
- Total exposure duration:
- 96 h
- Test temperature:
- 14 C
- pH:
- 7.8 - 8.0
- Dissolved oxygen:
- > 83%
- Salinity:
- Natural sea water
- Nominal and measured concentrations:
- The dose level was set at the concentration known to be toxic to other organisms under animal welfare rules.
Maximum concentration 4 mg/l as 7% actives (0.28 mg/l actives) - Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- 7% actives
- Basis for effect:
- mortality (fish)
- Details on results:
- No mortality seen at 4 mg/l of the 7% solution (ie 0.28 mg/l)
The dose level was set at the concentration known to be toxic to other organisms under animal welfare rules. - Validity criteria fulfilled:
- yes
- Conclusions:
- The results confirm that fish are less sensitive to the substance than other organisms tested.
Reference
Description of key information
A study performed on turbot confirmed that fish are less sensitive than other organisms. The dose level was set at the concentration known to be toxic to other organisms under animal welfare rules.
The read-across to the betaine is conisdered justified as the phosphate ester is considered likely to metabolise to form products that include phosphated betaines.
Evidence shows that fish are more tolerant to the class of substance than algae and further animal testing is not justifed
Acute toxicity is predicted to be in the range of 1 - 10 mg/l
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2 mg/L
Additional information
The headline result is from a weight of evidence study on zebra fish
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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