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EC number: 606-883-4 | CAS number: 219921-94-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 January - 20 May 1999
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: A well established calculation method was used; the results is considered to be reliable.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- GLP compliance:
- not specified
- Type of method:
- other: Calculation method
Test material
- Reference substance name:
- (S)-3-Methyl-1-(2-piperidine-1-phenyl)butylamine compound with N-Acetyl-L-glutamic acid
- EC Number:
- 606-883-4
- Cas Number:
- 219921-94-5
- Molecular formula:
- C16-H26-N2 x C7-H11-N-O5
- IUPAC Name:
- (S)-3-Methyl-1-(2-piperidine-1-phenyl)butylamine compound with N-Acetyl-L-glutamic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): AGEE 623 Glutaminate; L-Glutamic acid, N-acetyl, compd. with (S)-alpha-(2-methylpropyl)-2-(1-piperidinyl)-benzenemethanamine
- Molecular formula (if other than submission substance): c16H26Nq*C7H11NO5
- Molecular weight (if other than submission substance): 435.57 (246.4+189.17
- Structural formula attached as image file (if other than submission substance): see reference substance
- Physical state: solid white powder
- Analytical purity: 100% measured over area (4% of (R)-(-)-enantiomer
- Lot/batch No.: T29725
- Expiration date of the lot/batch: 31 december 1999
- Stability under test conditions: pure: see expiry date
- Storage condition of test material: in original container, at room temperature, in the dark
Constituent 1
Results and discussion
Vapour pressure
- Temp.:
- 25 °C
- Vapour pressure:
- < 0 Pa
Any other information on results incl. tables
The estimation of the vapour pressure of AGEE 623 Glutaminate was based on the EEC directive 92/69,
Armex V, Part A, Methods for the determination of physico-chemical properties, A.4 "Vapour Pressure",
EEC Publication No. L383, December 1992; the OECD Guideline No. 104, "Vapour Pressure", adopted
July 27, 1995 and the Product Properties Test Guideline OPPTS 830.7950 ofthe United States Enviroment
Proteerion Agency (EPA), August 1996.
AGEE 623 Glutaminate contains two components (see mo1ecular structure). The theoretical boiling point
for each component was evaluated using the procedure as described in this report, but only the component
with the lowest boiling point was used for the further estimation of the vapour pressure.
The 1owest boiling point of the components of AGEE 623 Glutaminate was calculated to be 400 oc for the
structure-component of (S)-alpha-(2-methylpropyl)-2-(1-piperidinyl)-benzenemethanamine using
Meissner's method.
The vapour pressure of this component was calculated to be 2 · 10-7 Pa.
During the determination of the melting point I melting range of AGEE 623 Glutaminate (IBACON project
4701180), a decomposition or reaction of AGEE 623 Glutaminate was observed at about 280 °C. This
experimental result confirm, that the boiling point of AGEE 623 G1utaminate is greater than 280 °C.
Therefore, the vapour pressure of AGEE 623 Glutaminate was also calculated using 280 oc as theoretical
boiling point of AGEE 623 Glutaminate. The vapour pressure, calculated from this decomposition temperature
of AGEE 623 Glutaminate resulted in a value of < 2 · 1 o-2 Pa.
Applicant's summary and conclusion
- Conclusions:
- In conclusion, the vapour pressure of AGEE 623 Glutaminate was estimated to be < 2*10E-07 Pa at 25 °C based on the boiling point calculated and using the Modified Watson Correlation. From this result, it can be concluded that the vapour pressure of AGEE 623 Glutaminate is too low to have any relevant effect on the environment.
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