Registration Dossier
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EC number: 271-347-5 | CAS number: 68541-50-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects up to the limit of water solubility (<0.05 mg/L)
Key value for chemical safety assessment
Additional information
The acute toxicity of
2-ethyl-2-(((1-oxoisooctadecyl)oxy)methyl)-1,3-propanediyl bis
(isooctadecanoate) (CAS 68541-50-4) to aquatic invertebrates was tested
by two available guideline studies. The key information is based on a
GLP study accomplished according to OECD guideline 202 (Marshall, 1996).
Daphnia magna were exposed to the test substance in a static test
system. After 48 hours an EC50 > 7.6 mg/L based on the measured
substance concentration was determined.
The results are supported by a second available study that was also
conducted according to OECD guideline 202 (Bouillon, 2010). Similar to
the key study a static test system was set up and the test organisms
(Daphnia magna) were exposed to the substance for 48 hours. In this
study the water accommodated fraction (WAF) of the test substance was
used for the preparation of the test solutions. Based on the loading
ratio of the test substance an EL50 > 0.11 g/L (nominal) was observed.
Therefore acute toxic effects on aquatic invertebrates are not expected within the range of the water solubility of the substance (< 0.05 mg/L).
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