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EC number: 272-940-1 | CAS number: 68921-45-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16 August 2012 to 20 November 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in accordance with OECD, EU and US EPA test guidelines in coompliance with GLP.
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- column elution method
- Water solubility:
- 0.706 mg/L
- Temp.:
- 20 °C
- pH:
- >= 6.9 - <= 7
- Details on results:
- Preliminary test
The content of test substance dissolved in the water sample after one centrifugation step was 1.99 mg/l.
Main study
The coefficient of variation (CV) (n = 10) was ≤ 30% at both flow rates. It demonstrated that the system was equilibrated at all flow rates.
The maximum difference (MD) on the mean values of the samples at both flow rates was also ≤ 30%. Based on this, the water solubility of the test substance is given as the mean value of these measurements.
The turbidity of the eluates was < 0.2 NTU. According to this, no undissolved particles were detected in the eluates.
No test substance was detected in the samples from the blank column, except for one sample in which a concentration of 0.000113 mg/l was measured. - Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of the test substance at 20°C was 0.706 mg/l. - Executive summary:
The aim of the study is to determine the following physico-chemical property for Benzenamine, N-phenyl-, reaction products with styrene and 2,4,4-trimethylpentene: Water solubility, using the following guidelines:
European Community (EC), EC no. 440/2008, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.6: “Water Solubility”, Official Journal of the European Union no. L142, May 31, 2008.
Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no. 105: "Water Solubility", July 27, 1995.
United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7840: "Water Solubility: Column Elution Method; Shake Flask Method", March 1998.
The column elution method was applied for the determination of the water solubility of Benzenamine, N-phenyl-, reaction products with styrene and 2,4,4-trimethylpentene.
The water solubility of the test substance at 20°C was 0.706 mg/l.
The pH of the aqueous samples was 6.9 – 7.0.
Reference
Main Study – water solubility of test substance
Flow rate
[ml/h] |
Sample no. |
Concentration analysed |
pH |
||||
Individual [mg/l] |
Mean1[mg/l] |
CV [%] |
Mean2[mg/l] |
MD [%] |
|||
24 |
1 |
0.4263 |
0.677 |
19 |
0.706 |
8.2 |
7.0 |
|
2 |
0.4503 |
|
|
|
|
|
|
3 |
0.4713 |
|
|
|
|
|
|
4 |
0.4943 |
|
|
|
|
|
|
5 |
0.609 |
|
|
|
|
|
|
6 |
0.569 |
|
|
|
|
|
|
7 |
>14 |
|
|
|
|
|
|
8 |
0.846 |
|
|
|
|
|
|
9 |
0.571 |
|
|
|
|
|
|
10 |
0.789 |
|
|
|
|
|
12 |
1 |
0.726 |
0.734 |
4.8 |
|
|
6.9 |
|
2 |
0.815 |
|
|
|
|
|
|
3 |
0.710 |
|
|
|
|
|
|
4 |
0.778 |
|
|
|
|
|
|
5 |
0.736 |
|
|
|
|
|
|
6 |
0.725 |
|
|
|
|
|
|
7 |
0.724 |
|
|
|
|
|
|
8 |
0.710 |
|
|
|
|
|
|
9 |
0.714 |
|
|
|
|
|
|
10 |
0.705 |
|
|
|
|
|
1Mean of the concentrations obtained at one flow rate.
2Mean of the concentrations obtained at both flow rates
3This value was not used for calculation of the mean because the system had not reached equilibrium yet
4This value was not used for calculation of the mean because this value was obtained by extrapolation of the calibration curve.
Description of key information
Key value determined using EU Method A6, OECD guideline 105 and US EPA test guideline OPPTS 830.7840.
Key value for chemical safety assessment
- Water solubility:
- 0.706 mg/L
- at the temperature of:
- 20 °C
Additional information
The column elution method was applied for the determination of the water solubility of Benzenamine, N-phenyl-, reaction products with styrene and 2,4,4-trimethylpentene.
The water solubility of the test substance at 20°C was 0.706 mg/l.
The pH of the aqueous samples was 6.9 – 7.0.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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