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Diss Factsheets
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EC number: 279-505-5 | CAS number: 80584-91-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- EL
- Analytical monitoring:
- yes
- Details on sampling:
- - Sampling method: algae separated by centrifugation before analysis
- Vehicle:
- no
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
- Details on test organisms:
- TEST ORGANISM
- Strain: G. Brinkmann 1953/SAG86,81
- Source: Institute of Botany, Slovak Academy of Sciences, Bratislava, Slovak Republic
- Method of cultivation: inoculum culture prepared 3 days before test start. Conditions same as under test. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
- Test temperature:
- 22 - 24 °C
- pH:
- 7.98 - 8.16
- Nominal and measured concentrations:
- Initial concentrations: 64, 128, 256, 512, 1024, 2048, 3000 mg/L (nominal)
Measured concentrations at start and end of the test: between -0.27% and +9.91% of nominal - Details on test conditions:
- TEST SYSTEM
- Test vessel: 50 mL volume in 150 mL flasks
- Type: closed with air-permeable stoppers
- Materia: glass or other chemically inert material
- Initial cells density: 4160 cells/mL
- No. of vessels per concentration (replicates): 3
- No. of vessels per control (replicates): 6
GROWTH MEDIUM
- Standard medium used: yes, according to OECD
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Sörensen buffer
- Intervals of water quality measurement: pH measured at beginning and end of test
OTHER TEST CONDITIONS
- Sterile test conditions: yes
- Adjustment of pH: stock solution adjusted with 1 N NaOH to pH 8.04
- Photoperiod: continuous illumination
- Light intensity and quality: 8470 - 8590 lux, cool white light, effective wavelength 400 - 700 nm - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- 145 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: 95% CI: 115-181 mg/L
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 3 285 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: 95% CI: 2619-4119 mg/L
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 452 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Remarks on result:
- other: 95% CI: 247-825 mg/L
- Results with reference substance (positive control):
- - 72 h-ECr10: 0.32 mg/L (mean of 3 determinations)
- 72 h-ECr50: 0.81 mg/L (mean of 3 determinations) - Reported statistics and error estimates:
- y
- Validity criteria fulfilled:
- yes
- Executive summary:
A growth inhibition test of TC to the algae Desmodesmus subspicatus was performed according to OECD 201. After 72 h of exposure, the ECr10 was determined to be 145 mg/L and the ECr50 to be 3285 mg/L.
Reference
Growth data:
Nominal concentration |
Inhibition of growth rate |
Inhibition of biomass |
64 |
1.00 |
4.4 |
128 |
6.71 |
21.2 |
256 |
18.11 |
42.3 |
512 |
25.66 |
60.8 |
1024 |
34.24 |
72.3 |
2048 |
43.65 |
76.9 |
3000 |
50.03 |
83.9 |
Description of key information
A 72 h growth inhibition test of TC to the algae Desmodesmus subspicatus was performed according to OECD 201.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 3 285 mg/L
- EC10 or NOEC for freshwater algae:
- 145 mg/L
Additional information
The EC50 (effect: growth rate) was determined to be 3285 mg/L.
The EC50 (effect: biomass) was determined to be 452 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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