Registration Dossier
Registration Dossier
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EC number: 808-257-8 | CAS number: 749927-69-3
Density
Administrative data
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06 AUG 2020 to 25 SEP 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Version / remarks:
- March 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Version / remarks:
- October 2012
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- Version / remarks:
- June 2002
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- air comparison pycnometer (for solids)
Test material
- Reference substance name:
- 4-Bromo-2-fluoro-N-methylbenzamide
- EC Number:
- 808-257-8
- Cas Number:
- 749927-69-3
- Molecular formula:
- C8H7BrFNO
- IUPAC Name:
- 4-Bromo-2-fluoro-N-methylbenzamide
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- lot/batch number of test material: FFP-106-200011
- Expiry date: 17 March 2021 (retest date)
- Physical Description: Almost white powder
- Purity: 99.0%
- Purity test date: 21 MAR 2020
- Purity correction factor: no
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature
- Stability under storage conditions: no data
- Stability under test conditions: no data
- Solubility and stability of the test item in the solvent/vehicle: no data
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
The test item was dried in a desiccator under vacuum using silicagel as the drying agent at 21.8 ± 3.3°C protected from light for 95 hours
Results and discussion
Densityopen allclose all
- Key result
- Type:
- density
- Density:
- 1.78 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: The individual measurements were obtained with an accuracy of < 0.02 g/cm³. According to the guideline, the density of the test item is given as the mean value
- Key result
- Type:
- relative density
- Density:
- 1.78
- Temp.:
- 20 °C
Any other information on results incl. tables
The results of the tests on the determination of the density of the test item are given in the table below
Experiment | Test 1 | Test 2 |
Test item mass (g) | 18.7396 | 18.7409 |
Test item volume (cm³) | 10.2914 | 10.2647 |
10.4941 | 10.5265 | |
10.4983 | 10.5129 | |
10.5008 | 10.5223 | |
10.5240 | 10.5156 | |
Mean test item volume (cm³) | 10.5043 ± 0.0134 | 10.5193 ± 0.0062 |
Density [g/cm³] | 1.784 | 1.782 |
Mean density [g/cm³] | 1.78 | |
Applicant's summary and conclusion
- Conclusions:
- A gas comparison stereopycnometer was used for the determination of the density and relative density of JNJ-61789975-AAA (T003669).
The density of the test item at 20ºC was 1.78 g/cm³ (1.78 x 10³ kg/m³).
The relative density was 1.78.
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