Phenol, mono- + distyrenated (MSP+DSP)

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Study based on accepted scientific standards

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Principles of method if other than guideline:

Preparation of the water-accommodated fraction (WAF) and determination by TOC measurement

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

- Name of test material (as cited in study report): Novares LS 500
- Source and lot/batch No.of test material: RÜTGERS Germany GmbH, batch No. 24430
- Composition of test material: composition is specified in IUCLID Sect. 13 - Assessment reports under Certificate of Analysis_Novares LS 500_phenol, styrenated
- Substance type: organic
- Stability under test conditions: no measured data; based on chemical structure assumed to be stable
- Storage condition of test material: room temperature, exclusion of light

Key result

Water solubility:

27.25 other: mg TOC/L (initial average, n = 3, time 0)

Conc. based on:

test mat. (dissolved fraction)

Remarks:

measured as T'OC

Loading of aqueous phase:

100 mg/L

Incubation duration:

24 h

Temp.:

20 °C

pH:

ca. 8

Water solubility:

26.81 other: mg TOC/L (average after storage, n = 3, time 48 h)

Conc. based on:

test mat. (dissolved fraction)

Remarks:

measured as TOC

Loading of aqueous phase:

100 mg/L

Incubation duration:

24 h

Temp.:

20 °C

pH:

ca. 8

Details on results:

Solubility data relate to loading of 100 mg TS/L:
Single values (time 0): 27.07; 27.31; 27.36 mg C/L
Single values (time 48 h): 26.76; 26.83; 26.85 mg C/L
Control 0.0 mg C/L
Limit of Quantification: 0.01 mg/L

Description of key information

In two tests, the water solubility of phenol, styrenated was tested analysing the substance concentration in water accommodated fractions. Substance concentrations at different loadings were variable. The highest concentration without any indication of undissolved material was taken as solubility limit.

Key value for chemical safety assessment

Water solubility:

31.8 mg/L

at the temperature of:

20 °C

Additional information

Water solubility of phenol, styrenated was determined in the course of aquatic toxicity testing. Water accommodated fractions were prepared for different tests by mixing various amounts of test substance with dilution water (reconstituted water). The aqueous phase was carefully separated and the concentration in the aqueous phase determined by measurement of the TOC values. The highest concentration measured without any indication of not dissolved test material was taken as water solubility of the test substance phenol, styrenated.

 

Data source	SGS Fresenius (2007)	BiLaCon (2000)
Load [mg TS/L]	100	1	10	100
concentration meas. [mg TOC/L]	27.25	0.5	4.5	40
concentration [mgTS/L]	31.8	0.58	5.25	46.7
Indication of non dissolved material	no	no	no	slightly turbid

 

Aqueous concentrations of TOC were converted to test substance concentrations using a carbon content of 85.66% for the test substance (calculated from molecular weights and percentage of test substance components).

 

From the preceding data, the water solubility of phenyl, styrenated is taken as 31.8 mg/L.