Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 611-173-2 | CAS number: 54605-02-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 July 2016
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- GLP compliance:
- no
- Other quality assurance:
- ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
- Type of method:
- thermal analysis
- Remarks:
- Differential Thermal Analysis (DTA) / Differential Scanning Calorimetry (DSC)
- Key result
- Melting / freezing pt.:
- >= 100 - <= 130 °C
- Decomposition:
- yes
- Remarks on result:
- other: mean of two determinations in an open crucible
- Conclusions:
- The melting range lies between 100 and 130°C and no pressure was reported.
The study is regarded as valid, only the heating rate of the sample is higher than requested by the OECD. This is however not regarded as relevant to the outcome of the study. - Executive summary:
A differential thermoanalysis method (DTA) was used to determine the melting point which conforms with the procedure Test method A.1, "Determination of the melting point", described in the EC-Guideline. The melting temperature was observed in a range between 100 and 130 °C (mean of two determinations in an open crucible). Endothermic effects were visible already at 65 °C. These effects lead to the assumption that, while melting, transformation and decomposition could occurre. In the closed crucible no melting could be observed. Bromhydrin-valerat recrystallized after the melting process. In the open crucible the residue was a light orange powder. In the closed crucible the residue was a dark red-brownish melt which indicates transformation of the substance.
Reference
RESULTS:
1. Thermal stability and decomposition:
- At room temperature the test item is a powdery solid
- Between approx. 65 °C – 140 °C an endothermic phase could be detected which indicates the melting range
- After the melting process an endothermic phase between 145 and 160 °C which went over directly to a exothermic phase between approx. 160 -215 °C was observed; this exothermic phase indicates transformation and decomposition, respectively, of the test item
2. Melting Point:
- Endothermic effects were visible already at 65 °C (These effects lead to the assumption that, while melting, transformation and decomposition could occurre)
- In the closed crucible no melting could be observed
The test item recrystallized after the melting process:
- In the open crucible the residue was a light orange powder
- In the closed crucible the residue was a dark red-brownish melt which indicates transformation of the substance
Validity criteria for the measurement of the melting point:
Target condition according to guideline: | Actual condition according to the study: | Validity criteria met: |
The heating rate should not exceed 2 K/min. | Heating rate 5 K/min. | No |
The mean of at least two measurements which are in the range of the estimated accuracy is reported as the melting temperature. | Two values were determined, in a closed crucible. | Yes |
If the substance decomposes or sublimes before the melting temperature is reached, the temperature at which the effect is observed shall be reported. | The test substance was heated up to a temperature of 130°C - no melting was observed in closed crucible. | Yes |
Description of key information
The melting range lies between 100 and 130 °C and no pressure was reported.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 115 °C
Additional information
Endothermic effects were visible already at 65 °C. These effects lead to the assumption that, while melting, transformation and decomposition occurred. In the closed crucible no melting could be observed. Bromhydrin-valerat recrystallized after the melting process.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.