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EC number: 953-797-0 | CAS number: 210300-09-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- Laser scattering/diffraction
Test material
- Reference substance name:
- 3-hydroxy-4-methoxypyridine-2-carboxylic acid
- Cas Number:
- 210300-09-7
- Molecular formula:
- C7H7NO4
- IUPAC Name:
- 3-hydroxy-4-methoxypyridine-2-carboxylic acid
Constituent 1
- Specific details on test material used for the study:
- Substance name: HMPCA
Lot #: EXP-16-BK7259 (TSN317010)
Purity: 100%
Results and discussion
- Mass median aerodynamic diameter:
- 55 µm
Particle sizeopen allclose all
- Key result
- Percentile:
- other: d(0.1)
- Mean:
- 31 µm
- Remarks on result:
- other: diameter where 90% of the distribution is above and 10% is below
- Key result
- Percentile:
- other: d(0.5)
- Mean:
- 55 µm
- Remarks on result:
- other: diameter where 50% of the distribution is above and 50% is below. The is referred to as the Mass Median Diameter (MMD)
- Key result
- Percentile:
- other: d(0.9)
- Mean:
- 96 µm
- Remarks on result:
- other: diameter where 10% of the distribution is above and 90% is below
Applicant's summary and conclusion
- Conclusions:
- The test substance was determined to have d(0.1), d(0.5) and d(0.9) values of 31, 55 and 96 μm, respectively.
- Executive summary:
A study was conducted to determine the particle size distribution of the test substance.
The particle size distribution was assessed using a technique based on laser diffraction in accordance with CIPAC MT 187.
The test substance was determined to have d(0.1), d(0.5) and d(0.9) values of 31, 55 and 96 μm, respectively.
d(0.1) is the diameter where 90% of the distribution is above and 10% is below.
d(0.5) is the diameter where 50% of the distribution is above and 50% is below. The is referred to as the Mass Median Diameter (MMD).
d(0.9) is the diameter where 10% of the distribution is above and 90% is below.
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