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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07/04/2020 to 15/05/2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
2009
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Specific details on test material used for the study:
Batch TROD7
Mass median aerodynamic diameter:
52.9 µm
Geometric standard deviation:
3.135
Key result
Percentile:
D10
Mean:
10.7 µm
St. dev.:
0.211
Key result
Percentile:
D50
Mean:
44.1 µm
St. dev.:
0.607
Key result
Percentile:
D90
Mean:
170 µm
St. dev.:
3.49
Conclusions:
The particle size distribution of the test item was determined by means of Laser Diffraction Analysis using the medium volume (wet) module (MVM).
The D50 of the test item was determined to be 44.1 μm, the D10 was 10.7 μm and the D90 was 170 μm. The MMAD of the test item, for the relative density and the mean d50, was calculated to be 52.9 μm. Volume of sample < 10.00 μm was determined to be 8.77% (< 9.86 μm).
Executive summary:

The particle size distribution of the test item was determined by means of Laser Diffraction Analysis using the medium volume (wet) module (MVM).

The D50 of the test item was determined to be 44.1 μm, the D10 was 10.7 μm and the D90 was 170 μm. The MMAD of the test item, for the relative density and the mean d50, was calculated to be 52.9 μm. Volume of sample < 10.00 μm was determined to be 8.77% (< 9.86 μm).

Description of key information

The D50 of the test item was determined to be 44.1 μm, the D10 was 10.7 μm and the D90 was 170 μm. The MMAD of the test item, for the relative density and the mean d50, was calculated to be 52.9 μm. Volume of sample < 10.00 μm was determined to be 8.77% (< 9.86 μm).

Additional information