Registration Dossier
Registration Dossier
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EC number: 947-879-5 | CAS number: 2475232-73-4
Endpoint summary
Administrative data
Description of key information
Acute toxicity to freshwater fish (Oncorhynchus mykiss): 96-hour LL50 >100 mg/L, OECD TG 203 (Eckenstein 2020)
Acute toxicity to freshwater invertebrates (Daphnia magna): 48-hour EL50 >100 mg/L, OECD TG 202 (Eckenstein 2020)
Toxicity to freshwater algae (Pseudokirchneriella subcapitata): 72-hour ErC50 >54 µg/L, 72-hour NOErC = 16 µg/L, OECD TG 201 (Eckentstein 2020)
Activated sludge respiration inhibition: 3 -hour NOEC = 1000 mg/L, OECD TG 209, Eisner 2020
Additional information
The toxicity of the substance to aquatic freshwater organisms from three trophic levels was tested under GLP to the relevant OECD guidelines. No adverse effects on freshwater fish (rainbow trout) and invertebrates (waterflea) were seen at the highest nominal loading rates of 100 mg/L, corresponding to mean measured concentrations of 95 µg/L in the fish study and 54 µg/L in the invertebrate study. The growth rate of freshwater green algae was reduced over the study period of 72 hours in the algal toxicity study. The 72-hour ErC50 and ErC10 values were determined to be >54 µg/L, and the 72-hour NOErC was 16 µg/L.
Considering all available data, a classification of the substance for acute aquatic toxicity under Regulation (EC) No. 1278/2008 is not warranted. However, based on the weak inhibitory effect on algal growth rate and considering that the substance is not readily biodegradable, a classification under Regulation (EC) No. 1278/2008 for chronic aquatic toxicity Cat. 1, H410, is considered appropriate.
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