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EC number: 617-694-1 | CAS number: 85261-19-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- microbial inoculum concentration was 30 mg/L
Activated sludge was obtained from a sewage plant treating predominantly domestic sewage
(Nanjing Chengdong Sewage Treatment Plant).
The sludge was washed with basal mineral salt medium (BSM) by settling the sludge in a
graduated cylinder, decanting the supernatant liquid, replacing with fresh BSM, aerating, and
settling. The above washing process was repeated 3 times and was aerated until use.
Before use, the sludge was centrifuged one time (5000 r/min, 4 °C, 10 minutes) and the
supernatant liquid decanted. Thereafter, a small amount of the washed sludge was weighed and
then dried at 100°C until the weight of the dried sludge did not change significantly anymore.
Then the dry weight percentage of suspended solids (p) of the activated sludge was calculated to
be 8.97%. Finally 22.3 g wet sludge after centrifugation was mixed with 0.5 L BSM to obtain an activated sludge with a mixed liquor suspended solids level of 4
g/L. Cell density was determined to be 6.14x 108 CFU/L using microscope. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 31.8 mg/L
- Based on:
- test mat.
- Initial conc.:
- 30.4 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Reference substance:
- aniline
- Parameter:
- % degradation (O2 consumption)
- Value:
- 71.5
- Sampling time:
- 28 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 66.8
- Sampling time:
- 28 d
- Remarks on result:
- other: 10-day window
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The results show that under the experimental conditions, biodegradation of the test substance
(Glucamide 9 (GA9)) was71.5% at the end of test, and biodegradation was 66.8% within 10-day
window. - Executive summary:
Accordingto "Theguidelines forthe testing of chemicals",SEPA(HJ/T 153-2004),"The
Guidelines fortheTestingofChemicals, Degradation andAccumulation" (2ndedition), Beijing:
China EnvironmentalPress.2013, "Chemicals-Readybiodegradability-Manometric
respirometrytest" (GB/T21801-2008); andwith referenceto Procedure 301F ofthe"Guidelines
forTestingof Chemicals" ofthe OECD:"Manometric Respirometry Test"(1992),the ready
biodegradabilityofGlucamide9(GA9) was determined in a28-dayoxygen consumption test
(OECD301F)usingactivated sludge from adomestic waste watertreatmentplantas the source
of the microbialinoculum.
The initial concentration of the testsubstancein the reaction vessels was31.8mg/L and30.4
mg/L. The microbial inoculumconcentration(mixed liquorsuspendedsolids) was30mg/L.
During the test, the temperature was kept at (22±1)°C.The pH valueofthe content in the test
container was maintained between 6.84 and7.45.The totaloxygenuptake in the inoculum blank
was22.9mg O2/Lattheendof thestudy,ranged20~30mg O2/L.Biodegradationof the
referencesubstance, aniline,reached65.1%at 14 days (>60%).Thedifference between replicate
values was less than20%during thestudy.Biodegradation of inhibitioncontrolwas 40.7%at14
days(>25%), and the oxygen consumption by the testsubstanceisgreaterthan 60% of inoculum
blank during the test period, indicating that there was no inhibitioneffectto inoculum. Thus, the
test was considered valid.
Underthe valid conditions, biodegradation of the test substance (Glucamide 9 (GA9)) was 71.5%
at the end of the28-day study,and biodegradation was 66.8% within10-day window
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- May - June 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- yes
- Remarks:
- See Principles of method if other tahn guideline
- Principles of method if other than guideline:
- The second set of inoculum weights used to confirm the suspended solids concentration in the test vessels, as estimated by the first set of inoculum weights, were discarded prior to the final weights being completed. This did not impact the volume of inoculum added at test initiation.
On one day, the thermometer used for daily temperature monitoring displayed minimum and maximum temperatures outside the test temperatures range, due to loose batteries causing faulty readings. The thermometer continued to operate normally after being reset and batteries were secured. No facility issues occurred at this time to account for this temporary temperature fluctuation. - GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- Activated sludge from the Joint Abbotsford Mission Environmental Systems (JAMES) wastewater treatment plant, Abbotsford, BC
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 45 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Mean test Temperature: 21 °C
pH: 7.2 - 7.6
Photoperiod: 24-h dark (expect during daily readings)
Test vessels: 2L flat-bottomed glass media bottles fitted with stoppers
test volume: 1.5 L
2 replicates - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 57
- Sampling time:
- 28 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 52
- Sampling time:
- 28 d
- Remarks on result:
- other: with Nitrification Correction
- Results with reference substance:
- 86% after 28 days
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The test Item cannot be considered readily biodegradable under the test conditions as the Test Item did not surpass 60% biodegradation by the end of the 10-day windows (53%; 48% with nitrification correction). Due to the stringency of this test, test items which do not achieve pass levels may still be biodegradable in the environment.
- Executive summary:
The Test Item was tested to asses its degree of ready biodegradability using the procedures outlined in the Maxxam Study Plan which is based on the Standard Operating Procedure (SOP) for Ready Biodegradability: manomentric Respirometry test (OECD, 1992).
Referenceopen allclose all
Description of key information
Two studies according OECD Guideline 301F are available. In one Study a degradation of 57 % (52 after Nitrification Correction) was found. In the second (KEY Study) a degradation 71.5 % after 28 days and 66.8 % in 10 day window was found.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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