pymetrozine (ISO); (E)-4,5-dihydro-6-methyl-4-(3-pyridylmethyleneamino)-1,2,4-triazin-3(2H)-one

Boiling point

Administrative data

Endpoint:

boiling point

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is a solid which decomposes before boiling

Justification for type of information:

According to Regulation (EC) no. 1907/2006, Annex VII, 7.3, column 2, the study does not need to be conducted for substances which decompose before boiling. In a study according to the OECD TG 102 and in compliance with GLP, the melting temperature of the test substance was determined to be 217 °C, with decomposition observed around 190 °C.

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

13 Nov 1992 to 10 Mar 1993

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

May 1981

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

September 1984

Deviations:

no

GLP compliance:

yes

Type of method:

capillary method

Key result

Melting / freezing pt.:

217 °C

Decomposition:

yes

Decomp. temp.:

190 °C

Remarks on result:

other: Around 190 °C, a colour change was noted

Remarks:

Atm. pressure was not reported

Table: Results of the melting point determinations

Substance	Starting Temp. (°C)	Heating Rate / °C . min^-1	Melting point (°C)
Carbazole	243.0	0.2	245.8
	243.0	0.2	245.7
Average			245.75
Expected			245.3
Test substance	215.0	0.2	216.6
	215.0	0.2	216.5
	200.0	1.0	217.6
	200.0	1.0	217.2
	200.0	1.0	217.6
Average			217

The colour change was noted to occur at around 190 °C. The accuracy of the determination could have been influenced by the decomposition.

Conclusions:

The melting point of the test substance was determined to be 217.0 °C.

Executive summary:

The study was performed to determine the melting temperature of the test substance using the capillary method according to OECD TG 102 and in compliance with GLP. The mean melting temperature of the test substance was determined to be 217 °C, with a decomposition observed around 190 °C.