Registration Dossier
Registration Dossier
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EC number: 906-151-7 | CAS number: -
Endpoint summary
Administrative data
Description of key information
LD50 oral (rat), p-Cresol = 207 mg/kg bw
LD50 oral (rat), m-Cresol = 242 mg/kg bw
LD50 dermal (rat), p-Cresol = 750 mg/kg bw
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- not specified
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data from Supplier's Safety Data Sheet
- Species:
- rat
- Route of administration:
- oral: unspecified
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 242 mg/kg bw
- Based on:
- not specified
- Interpretation of results:
- Category 3 based on GHS criteria
- Endpoint:
- acute toxicity: oral
- Type of information:
- not specified
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data from Supplier's Safety Data Sheet
- Species:
- rat
- Route of administration:
- oral: unspecified
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 207 mg/kg bw
- Based on:
- not specified
- Interpretation of results:
- Category 3 based on GHS criteria
Referenceopen allclose all
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 207 mg/kg bw
- Quality of whole database:
- Reliability 4 (Data from supplier's Safety Data Sheet)
Acute toxicity: via dermal route
Link to relevant study records
- Endpoint:
- acute toxicity: dermal
- Type of information:
- not specified
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data from Supplier's Safety Data Sheet
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
- Type of coverage:
- not specified
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 130 mg/kg bw
- Based on:
- not specified
- Interpretation of results:
- Category 2 based on GHS criteria
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 750 mg/kg bw
- Quality of whole database:
- Reliability 4 (Data from supplier's Safety Data Sheet)
Additional information
Justification for classification or non-classification
Based on the available data reported in the supplier's Safety Data Sheet and the harmonized classification, the registered substance is classified Acute Tox cat. 3, H301 and Acute Tox cat. 3, H311 according to the classification criteria of GHS regulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
