Reaction mass of L-Glutamic acid, N-coco acyl derivs., monosodium salts and sodium hydrogen N-(1-oxooctadecyl)-L-glutamate

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

19 December 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

pour and tap (for solids)

Key result

Type:

pour density

Density:

0.453 g/cm³

Temp.:

20 °C

Key result

Type:

tap density

Density:

0.559 - 0.566 g/cm³

Temp.:

20 °C

Key result

Type:

density

Density:

> 453 - < 562 kg/m³

Temp.:

20 °C

Key result

Type:

relative density

Density:

> 0.453 - < 0.562 other: Dimensionless

Temp.:

20 °C

Determination of pour density

Run number	1	2
Mass of cylinder (g)	19.042	19.042
Volume of untapped sample in cylinder (mL)	10.0	10.0
Mass of cylinder and untapped sample (g)	23.567	23.567
Mass of sample (g)	4.525	4.525
Pour density of sample (g/cm3)	0.453	0.453

 

Determination of tap density

Run number	1	2
Mass of tapped material in cylinder (g)	8.1	8.0
Mass of cylinder and tapped sample (g)	23.567	23.567
Mass of sample (g)	4.525	4.525
Tap density of sample (g/cm3)	0.559	0.566

 

Conclusions:

Under the conditions of this study the pour density was 0.453 g/cm^3, and the tap density was 0.562 g/cm^3, therefore the density is between 453 and 562 kg/m^3 at 20 °C. The relative density is in the range of 0.453 to 0.562.

Executive summary:

The relative density of the test material was determined in accordance with the standardised guidelines OECD 109 and EU Method A.3, under GLP conditions.

The pour and tap density was performed after analysis using the pycnometer and hydrostatic methods were found to be unsuitable due to the test material being soluble in all the immersion liquids investigated.

In the pour and tap method, a known weight of the test material was put into a glass measuring cylinder and its volume was measured. The cylinder was then raised and allowed to fall vertically through a distance of 25 mm on to a rubber/cork pad. The volume was measured again after 100 ‘taps’.

Under the conditions of this study the pour density was 0.453 g/cm^3 and the tap density was 0.562 g/cm^3, therefore the density is between 453 and 562 kg/m^3 at 20 °C. The relative density is in the range of 0.453 to 0.562.

Description of key information

Under the conditions of this study the pour density was 0.453 g/cm^3 and the tap density was 0.562 g/cm^3, therefore the density is between 453 and 562 kg/m^3 at 20 °C. The relative density is in the range of 0.453 to 0.562.

Key value for chemical safety assessment

Relative density at 20C:

0.453

Additional information

The relative density of the test material was determined in accordance with the standardised guidelines OECD 109 and EU Method A.3, under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

The pour and tap density was performed after analysis using the pycnometer and hydrostatic methods were found to be unsuitable due to the test material being soluble in all the immersion liquids investigated.

In the pour and tap method, a known weight of the test material was put into a glass measuring cylinder and its volume was measured. The cylinder was then raised and allowed to fall vertically through a distance of 25 mm on to a rubber/cork pad. The volume was measured again after 100 ‘taps’.

Under the conditions of this study the pour density was 0.453 g/cm^3 and the tap density was 0.562 g/cm^3, therefore the density is between 453 and 562 kg/m^3 at 20 °C. The relative density is in the range of 0.453 to 0.562.