Registration Dossier
Registration Dossier
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EC number: 208-021-9 | CAS number: 505-84-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: read-across
- Justification for type of information:
- HYPOTHESIS FOR THE ANALOGUE APPROACH , SOURCE AND TARGET CHEMICAL(S), ANALOGUE APPROACH JUSTIFICATION and DATA MATRIX are provided in the attached document.
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Joint meeting of the chemicals committee and the working party on chemical, pesticides and biotechnology, Guidance on grouping of chemicals, ENV/JM/MONO(2007)28
- GLP compliance:
- no
- Key result
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Conc. based on:
- test mat.
- Validity criteria fulfilled:
- yes
- Conclusions:
- Propylal predicted EC50(3h) is >100 mg/L.
- Executive summary:
A read-across approach was developped to derive Propylal EC50. The suggested source chemicals , i.e. dioxolane, was considered sufficient structurally, physicochemical and reactivity similar to the target chemical, i.e. propylal, to apply the read-across approach. The activated sludge respiration inhibition test was predicted EC50(3h) > 100 mg/L.
Reference
Description of key information
Key value for chemical safety assessment
- EC50 for microorganisms:
- 100 mg/L
Additional information
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