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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Surface tension
Administrative data
- Endpoint:
- surface tension
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because water solubility is below 1 mg/L at 20°C
Cross-reference
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Endpoint:
- transformation / dissolution of metals and inorganic metal compounds
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-08-08 to 2017-10-20
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Series on Testing and Assessment No. 29 (23-Jul-2001): Guidance document on transformation/dissolution of metals and metal compounds in aqueous media
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- signed 2016-05-31
- Type of method:
- flask method
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.341 µg/L
- Element analysed:
- Al
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH = 6, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of all replicates < LOD: 0.341 µg/L
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 0.533 µg/L
- Element analysed:
- Al
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH = 8, separation of solid phase by filtration 0.2 µm
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.161 µg/L
- Element analysed:
- Al
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH = 6, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of all replicates < LOD: 0.161 µg/L
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.161 µg/L
- Element analysed:
- Al
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH = 8, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of all replicates < LOD: 0.161 µg/L
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.161 µg/L
- Element analysed:
- Al
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH = 6, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of all replicates < LOD: 0.161 µg/L
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.161 µg/L
- Element analysed:
- Al
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH = 8, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of all replicates < LOD: 0.161 µg/L
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 0.357 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH = 6, separation of solid phase by filtration 0.2 µm
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.085 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH = 8, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- not determinable
- Remarks:
- not distinguishable from blank
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 1.34 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH = 6, separation of solid phase by filtration 0.2 µm
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.035 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH = 8, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of all replicates < LOD: 0.035 µg/L
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.035 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH = 6, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of replicates < LOD: 0.035 µg/L
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.035 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH = 8, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of all replicates < LOD: 0.035 µg/L
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 0.063 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH = 6, separation of solid phase by filtration 0.2 µm
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.123 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH = 8, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of all replicates at least < LOQ: 0.123 µg/L
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.123 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH = 6, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of all replicates at least < LOQ: 0.123 µg/L
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.123 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH = 8, separation of solid phase by filtration 0.2 µm
- Remarks on result:
- other:
- Remarks:
- conc. of all replicates at least < LOQ: 0.123 µg/L
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 0.103 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH = 6, separation of solid phase by filtration 0.2 µm
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 0.04 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH = 8, separation of solid phase by filtration 0.2 µm
- Details on results:
- Solution pH, oxygen concentrations, temperature
The temperature of the thermostatically controlled room was recorded with a data logger. The mean temperature was 21.3 ± 0.3 °C. The solution pH remained relatively constant for the pH 6 treatment for the method blank vessels (6.15 – 6.37) as for the sample vessels (5.93 – 6.37).
Oxygen levels in all test vessels pH 6 were in the range recommended by the OECD Test Guidance 29 during the test: above 70 % of oxygen saturation at 8.5 mg/L (70 % of 8.5 mg/L = 6 mg/L). The solution pH for the pH 8 treatment showed a decrease of the pH during the test in the method blanks as well as in the sample vessels. In the test item vessels the pH was in the range of 7.64 – 7.93 and in method blank vessels the pH was in the range of 7.66 – 7.84. Oxygen levels in all test vessels pH 8 were in the range recommended by the OECD Test Guidance 29 during the test: above 70 % of oxygen saturation at 8.5 mg/L (70 % of 8.5 mg/L = 6 mg/L)
Analytical measurements: Within and between vessel variations of elemental concentrations (Fe, Ti, Al)
Within and between vessel variations are not always in compliance with the guidance for the tests. For these samples the observed variations of > 20 % (between-vessel) or > 10 % (within-vessel) are probably due to the low dissolution and the majority of measurements being close to – or below – the respective quantification limit of the method - Conclusions:
- The transformation/dissolution test (OECD Series on Testing and Assessment Number 29, 2001) of "Titanium, iron and aluminium pseudobrookite and rutile (Pigment Black 12)" at a loading of 1 mg/L at pH 6 and 8, performed for 28d, resulted in maximum quantified Al concentrations of 0.533 µg/L (pH = 8, 28d), maximum Fe concentrations of 0.357 µg/L (pH = 6, 28d) als well as maximum Ti concentrations of 0.063 µg/L (pH = 6, 28d). Thus, the extent to which "Pigment Titanium, iron and aluminium pseudobrookite and rutile (Pigment Black 12)" can produce soluble available ionic and other metal-bearing species in aqueous media is limited.
Method validation summary (ICP-OES)
Limits of detection (LODs), limits of quantification (LOQs) and correlation coefficients (r)
Limits of detection (LOD) within all measurement series: 0.161 -0.341 μg Al / L, 0.035 - 0.085 µg / L Fe
Limits of quantification (LOQ) within all measurement series: 0.482 - 1.02 μg Al / L, 0.106 - 0.255 µg / L Fe
Correlation coefficients (r) within all measurement series: > 0.999926 (Al calibration), > 0.999868 (Fe calibration)
Mean recovery of fortified samples (concentration range 6 - 160 µg, n > 5): 95,2 - 119 % (Al fortification), 95 - 108 % (Fe fortification)
Mean recovery for certified reference material TMDA-52.4 (lot no. 0615, Environment Canada): 99.9 - 104 % (Al measurement, n = 15), 98.4 - 103 % (Fe measurement, n = 13)
date |
Chosen wavelength [nm] |
LOD |
LOQ |
correlation coefficient |
Sum of quality assurance samples |
Recovery of quality assurance samples [%] |
August 17, 2017; measurement of test samples |
Al: 167.019* Fe: 238.204* |
Al: 0.161 Fe: 0.035 |
Al: 0.482 Fe: 0.106 |
Al: 0.999926 Fe: 0.999868 |
Al: 17 Fe: 17 |
Al: 88.2 Fe: 88.2 |
date |
Chosen wavelength [nm] |
LOD |
LOQ |
correlation coefficient |
Sum of quality assurance samples |
Recovery of quality assurance samples [%] |
September 29, 2017; measurement of test samples (28 d) and method blank samples (28 d) |
Al: 167.019* Fe: 238.204* |
Al: 0.341 Fe: 0.085 |
Al: 1.02 Fe: 0.255 |
Al: 0.999974 Fe: 0.999940 |
Al: 26 Fe: 26 |
Al: 88.5 Fe: 92.3 |
date |
Chosen wavelength [nm] |
LOD |
LOQ |
correlation coefficient |
Sum of quality assurance samples |
Recovery of quality assurance samples [%] |
October 20, 2017; measurement of mass balance samples – filters and test vessels pH 6 and 8 |
Al: 394.401* Fe: 260.709* Ti: 307.866* |
Al: 2.16 Fe: 0.300 Ti: 0.149 |
Al: 6.48 Fe: 0.900 Ti: 0.448 |
Al: 0.999942 Fe: 0.999965 Ti: 0.999923 |
Al: 21 Fe: 21 Ti: 21 |
Al: 81.0 Fe: 95.5 Ti: 100 |
Method validation summary (ICP-MS)
Limits of detection (LODs), limits of quantification (LOQs) and correlation coefficients (r)
Limits of detection (LOD) within all measurement series: 0.041 μg Ti / L.
Limits of quantification (LOQ) within all measurement series: 0.123 μg Ti / L.
Correlation coefficients (r) within all measurement series: > 0.9997
Recovery of fortified samples (n = 4): 106 -110 %
Mean recovery of certified reference material TMDA-52.4 (lot no. 0615, Environment Canada): 102% (n=5)
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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