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EC number: 824-801-7 | CAS number: 1093628-27-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In order to predict effects of chemicals in an aquatic environment, the toxicity to freshwater algae was assessed. The algal toxicity was determined in the Algal Growth Inhibition test in accordance with OECD 201, EEC and ISO 8692 test guidelines and with the OECD Principles of Good Laboratory Practice. The guidelines were slightly modified to ensure good growth and pH control of the cultures.
The green algae Pseudokirchneriella subcapitata (formerly known as Se/enastrum capricomutum) was exposed to the following nominal concentrations: 0, 4.3, 9.4, 20.7, 45.5 and 100 mg/L prepared from the 0.1 g/L stock solution of Witconate P-1460. The toxicity of Witconate P-1460 to an exponentially growing culture of P. subcapitata was determined over an exposure period of 72 hours. The EbC50 and ErC50 (0 - 72 h) are 46.3 (95% confidence limits: 26.4 - 89.1) and >100 mg/L, respectively. The NOEC and LOEC are 9.4 mg/I and 20.7 mg/I, respectively. The test was conducted in a mineral salts medium in a climatized illuminated orbital incubator. The maximum variation in pH in the test media was 1.0 pH unit.
The definitive test is valid as shown by the increase of the extinction of the control over 72 h by a factor of 134.
The results of the chemical analyses show that the initial concentrations in the test solutions are close to the nominal (expected) concentrations. A decrease of >70% of test substance concentration during the 72 hours of testing is observed at 4.6 and 20.7 mg/L. No decrease is observed at 100 mg/L. Degradation and sorption to glassware of the test substance are both unlikely reasons for the decrease because at 100 mg/L no significant decrease of the test concentration is observed. For chemical analyses, the samples were filtered to remove the algae. The most obvious reason for the observed decrease is therefore adsorption of the test substance to the algae. If no degradation or sorption to glassware occurred, the algae in the test vessels were fully exposed to the test substance. Therefore the nominal test concentrations were used to calculate the effects.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 46.3 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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