Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-737-3 | CAS number: 149-32-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 02/05/2006-01/06/2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Erythritol
- EC Number:
- 205-737-3
- EC Name:
- Erythritol
- Cas Number:
- 149-32-6
- Molecular formula:
- C4H10O4
- IUPAC Name:
- butane-1,2,3,4-tetrol
Constituent 1
- Specific details on test material used for the study:
- Sponsor number : Lot No. of test item : 5005108
Hydrotox number : 06/2501
Appearance : white crystalline powder
Storage conditions : keep tightly closed in a dry and cool place
Durability : 08/2008
Solubility in water : soluble
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic (adaptation not specified)
- Details on inoculum:
- Secondary effluent from the municipal wastewater treatment plant Breisgauer Bucht was used as inoculum (0.1 ml per litre). The treatment plant clarifies predominantly domestic wastewater of the region of Freiburg and has a capacity of 600.000 inhabitant equivalents. The inoculum was aerated and incubated in darkness for 24 h (temperature 20.0°C). The pH of the inoculum was 8.4.
0.7 mL were added to the mineral medium for the experimentation. This corresponds to a test concentration of 2 mg/I. - Duration of test (contact time):
- ca. 28 d
Initial test substance concentration
- Initial conc.:
- ca. 2 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium:
- Test temperature: 20-22°C
- pH: 7.1
- Continuous darkness: yes for 28d
- initial O2 concentration was 8.9 mg/L
TEST SYSTEM
- Culturing apparatus:
- Number of culture flasks/concentration: 6 bottles were filled (6 for the erythritol, 6 for the substance reference experiment, 6 for the blank)
- Method used to create aerobic conditions:
- Method used to create anaerobic conditions:
- Measuring equipment:
- Details of trap for CO2 and volatile organics if used:
- Other:
SAMPLING
The zero-time botties were analysed immediately after filling using the electrode method. On days 4, 7, 11, 14, 21 and 28 at Ieast duplicate botties were removed for determination of dissolved oxygen and pH. If the oxygen concentrations in duplicate botties differed more than 0.3 mg/I, a third bottie was measured to confirm data. At the end of the test dissolved oxygen concentration in ail remaining botties was measured.
CONTROL AND BLANK SYSTEM
- Inoculum blank: An aquarium was filled with 6 I minerai medium and 0.7 ml of inoculum was added. Then the volume was made up to 7 litres. The oxygen concentration, the temperature and the pH was measured. 21 bottles were filled
- Abiotic sterile control:
- Other:
Reference substance
- Reference substance:
- benzoic acid, sodium salt
- Remarks:
- Sodium acetate
Results and discussion
- Preliminary study:
- Not specified
- Test performance:
- Not specified
% Degradationopen allclose all
- Key result
- Parameter:
- other: % degradation is calculated : % deg BODx *100/ThOD
- Value:
- > 72
- Sampling time:
- 21 d
- Key result
- Parameter:
- other: % degradation is calculated : % deg BODx *100/ThOD
- Value:
- > 63
- Sampling time:
- 28 d
- Details on results:
- On day 28 the degradation extent slightly decreased to 63 %, which is caused by increase of oxygen depletion in the blank bottles.
BOD5 / COD results
- Results with reference substance:
- The reference compound sodium benzoate reached the pass level for ready biodegradability within 4 days. The pH was 7.1 at the beginning of the test.
Any other information on results incl. tables
Criteria
met for the validity of the study
> The
maximal deviations for the parallel oxygen measurements at the plateau
were < 20%.
> The
percentage degradation of the reference item met the criterion for
biological degradation after 4 days.
> The
oxygen concentration in the test bottles never fell below 0.5 mg/1.
> Oxygen
depletion in the blanks never exceed 1.5 mg 02/1
> The
temperature in the incubator during the test remained between 20.0°C and
22°C (inside ± 1°C constant)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Erythritol is readily biodegradable in the closed bottle test (OECD 301D).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.