Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-430-9 | CAS number: 106-75-2
Endpoint summary
Administrative data
Description of key information
Additional information
Oxydiethylene bis(chloroformate) rapidly hydrolyses in contact with water to form diethylene glycol (CAS 111 -46 -6), hydrogen chloride (CAS 7647-01-0) and carbon dioxide (CAS 124-38-9). Therefore, the relevant key aquatic toxicity data for both the parent substance and for the hydrolysis products diethylene glycol and hydrogen chloride are listed below. No aquatic toxicity data are available for carbon dioxide.
Short-term toxicity to fish:
Parent compound: 96-h LC50 = 1.78 mg/L (nom., L. idus; BASF AG, 1987)
The substance is acutely toxic to fish.
Hydrolysis product diethylene glycol: 96-h LC50 = 75200 mg/L (meas., P. promelas, similar to OECD 203; Geiger et al., 1990)
With high probability, the substance is acutely not harmful to fish.
Hydrolysis product HCl: 96-h LC50 = 4.92 mg/L (meas., C. carpio, OECD 203; OECD, 2002)
The substance is acutely toxic to fish (pH-dependent).
Long-term toxicity to fish:
No relevant and reliable data available.
Short-term toxicity to aquatic invertebrates:
Parent compound: no data
Hydrolysis product diethylene glycol: 24-h EC50 > 10000 mg/L (nom., D. magna; Bringmann & Kühn, 1982)
With high probability, the substance is acutely not harmful to aquatic invertebrates.
Hydrolysis product HCl: 48-h EC50 = 0.492 mg/L (meas., D. magna, OECD 202; OECD, 2002)
The substance is acutely very toxic to aquatic invertebrates (pH-dependent).
Long-term toxicity to aquatic invertebrates:
No relevant and reliable data available.
Growth inhibition to aquatic algae:
Parent compound: no data
Hydrolysis product diethylene glycol (weight-of-evidence): EC50 > 100 mg/L
With high probability, the substance is acutely not harmful to aquatic algae.
Hydrolysis product HCl: 72-h ErC50 = 0.492 mg/L; NOEC = 0.097 mg/L (OECD 201; OECD, 2002)
The substance is acutely very toxic to aquatic algae (pH-dependent).
Toxicity to microorganisms:
Parent compound: Pseudomonas putida: 17-h EC10 = 69 mg/L (nom., non-neutralised); 17-h EC10 = 8070 mg/L (nom., neutralised; growth inhibition; BUA, 1991); covering also effects from the hydrolysis products diethylene glycol and HCl
Hydrolysis product diethylene glycol: 3-h EC50 > 1000 mg/L (OECD 209, domestic activated sludge; Klecka et al., 1985)
Hydrolysis product diethylene glycol: 30-min EC20 > 1195 mg/L (ISO 8192, domestic activated sludge; Klecka et al., 1985)
An inhibition of the degradation activity of activated sludge is not expected when introduced to biological treatment plants in appropriately low concentrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
