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Diss Factsheets
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EC number: 259-653-7 | CAS number: 55466-76-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- Water samples were taken from the control and each replicate test vessel at 0 (fresh media), 24 and 96 (old media) hours.
- Vehicle:
- no
- Details on test solutions:
- Range-finding study conducted and based on this a limit test at 100 mg/L was conducted. For the definitive study, test material was dissolved directly in water with the aid of ultasonification. A 4000mg/L stock solution was prepared, which was then diluted to give a 100 mg/L test solution.
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- Fish were obtained from Brow Well Fisheries, UK. Fish acclimatised to test conditions from 1-13 November 2000. Feeding discontinued 24hrs pror to the start of the definitive study. Mean standard length of 4.2cm, mean weight of 0.96g. Loading rate 0.48 g bodyweight/litre.
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Test temperature:
- 14 ± 1°C
- pH:
- 7.1-7.9
- Dissolved oxygen:
- 9.3-10.2
- Salinity:
- Not applicalbe
- Nominal and measured concentrations:
- Exposed to a single concentration of 100 mg/L based on the results of the range finding test. Measured concentration remained near nominal, therefore LC50 values were based on nominal.
- Details on test conditions:
- Test vessel: 20 litre glass exposure vessels, covered to reduce evaporation
No of organisms per vessel: 10 fish per vessel
No of replicates per concentration: 2 replicates
Photoperiod: 16 hours light and 8 hours dark - Reference substance (positive control):
- not specified
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- No mortalities recorded
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 96 hour LC50 of ruthenium acetate to Oncorhynchus mykiss was reported to be >100 mg/L.
- Executive summary:
This study is GLP compliant and followed OECD guideline 203. A limit test at 100 mg/L was conducted. Test concentrations were analysed and were close to nominal, therefore the LC50 value is reported based on nominal concentration. It is suitable for use as a key study for this endpoint. The 96 hour LC50 of ruthenium acetate to Oncorhynchus mykiss was reported to be >100 mg/L.
Reference
Description of key information
The 96 hour LC50 of ruthenium acetate to Oncorhynchus mykiss was reported to be >100 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
Wetton and Mullee (2001) is GLP compliant and followed OECD guideline 203. A limit test at 100 mg/L was conducted. Test concentrations were analysed and were close to nominal, therefore the LC50 value is reported based on nominal concentration. It is suitable for use as a key study for this endpoint. The 96 hour LC50 of ruthenium acetate to Oncorhynchus mykiss was reported to be >100 mg/L.
This is supported by Jianying (2004), a guideline study considered suitable for use as a supporting study for this endpoint. A single nominal concentration of 100 mg/L was used. Test solutions were renewed, but test concentrations were not analytically verified. The 96 hour LC50 of ruthenium acetate to Zebrafish was determined to be >100 mg/L.
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