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EC number: 223-804-5 | CAS number: 4079-68-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- Version / remarks:
- September, 1984
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Golpanol DP
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic, non-adapted
- Duration of test (contact time):
- 28 d
- Initial conc.:
- >= 10 - <= 40 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- The test batches contain inorganic salts dissolved in distilled water and the test substance in a concentration of about 10 to max. 40 mg/L based on their carbon content. At certain intervals, a sample is taken and the dissolved organically bound carbon (= DOC) is determined. The experiment was performed in duplicate.
- Reference substance:
- not specified
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 73
- Sampling time:
- 28 d
- Remarks on result:
- other: calculated from 2 experiments
- Details on results:
- Biodegradation of the test substance was observed: After 7 days, the amount of DOC was decreased by 53% and 41% in replicate 1 and 2, respectively. After 28 days, DOC-content was decreased by 81% and 65% for replicate 1 and 2, respectively. After 28 days, the test substance was degraded for 73% (mean value). See 'Any other information on results incl. tables'.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable, but failing 10-day window
Reference
Measured DOC and inhibition throughout the test
Time |
Test substance replicate 1 |
Decrease (% degradation) |
Test substance replicate 2 |
Decrease (% degradation) |
Study initiation |
DOC = 21.6 mg/L |
--- |
DOC = 21.6 mg/L |
--- |
7 Days |
DOC = 10.3 mg/L |
53% |
DOC = 12.8 mg/L |
41% |
14 Days |
DOC = 6.6 mg/L |
70% |
DOC = 9.9 mg/L |
54% |
21 Days |
DOC = 4.7 mg/L |
78% |
DOC = 7.7 mg/L |
64% |
25 days |
DOC = 4.7 mg/L |
78% |
DOC = 7.7 mg/L |
64% |
28 Days |
DOC = 4.2 mg/L |
81% |
DOC = 7.6 mg/L |
65% |
Description of key information
The substance is readily biodegradable but failing 10-day window as observed in a Modified OECD Screening test according to OECD TG 301E.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable but failing 10-day window
Additional information
The biodegradation potential of the substance in water was determined in a screening study according to OECD TG 301E (Modified OECD Screening (mod. 301A)) (GLP not specified) (BASF, 1987). In this study, 10 to 40 mg/L test substance (expressed as DOC) was inoculated with non-adapted activated sludge from a predominantly domestic sewage treatment plant for 28 days under aerobic conditions. The DOC-content was determined after 7, 14, 21, 25 and 28 days incubation. The observed decrease in measured DOC-content was expressed as % degradation. After 7 days, the DOC-content was decreased by 53% and 41% in replicate 1 and 2, respectively. After 28 days, the DOC-content had decreased by 81% and 65%, respectively. The mean biodegradation after 28 days was calculated to be 73%. Based on the results, the substance is classified as readily biodegradable. The adaptation phase of the inoculum cannot be accurately determined due to the limited amount of determinations of DOC-content. Consequently, it cannot be determined if the 10-day window criterion was met.
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