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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 256-852-0 | CAS number: 50925-66-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
- Endpoint:
- toxicity to soil microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Although many publication note that Cr III is less toxic than Cr VI, this research covers the conversion of Cr VI to Cr III under microbial influence. The use of microbial innoculation is used in remdiation of Cr VI contaminiated soils and this paper considered tolerance to Cr VI.
The fact that the micro-organisms survive the Cr VI and then thrive in the Cr III enriched media demonstrates toxicity to Cr III to be significanty lower than Cr VI.
Cross-reference
- Reason / purpose for cross-reference:
- data waiving: supporting information
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 017
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EPA OPPTS 850.5100 (Soil Microbial Community Toxicity Test)
- Principles of method if other than guideline:
- The effect of Cr on Pseudomonas aeruginosa growth was checked by comparing the growth of Pseudomonas aeruginosa in medium containing certain concentration of chromium and in medium without chromium.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Potassium dichromate
- EC Number:
- 231-906-6
- EC Name:
- Potassium dichromate
- Cas Number:
- 7778-50-9
- Molecular formula:
- Cr2H2O7.2K
- IUPAC Name:
- Potassium dichromate
Constituent 1
- Specific details on test material used for the study:
- Specific details not provided
Sampling and analysis
- Analytical monitoring:
- yes
Test substrate
- Vehicle:
- yes
- Details on preparation and application of test substrate:
- Water
Test organisms
- Test organisms (inoculum):
- soil
Study design
- Total exposure duration:
- 24 h
Test conditions
- Test temperature:
- These plates were incubated at 37ºC
- Moisture:
- In water based media
- Details on test conditions:
- Nutrient agar used
- Nominal and measured concentrations:
- Nominal 0, 20, 50, 100, 150, 200 ppm
- Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 50 other: ppm
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Cell growth
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- ca. 50 other: ppm
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Cell growth
- Details on results:
- Pseudomonas aeruginosa grew normally up to at least 50 ppm of Cr (VI), and was killed at 100 ppm of Cr (VI)
Biotransformation efficiency of Cr (VI) into Cr (III)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Although many publication note that Cr III is less toxic than Cr VI, this research covers the conversion of Cr VI to Cr III under microbial influence. The use of microbial innoculation is used in remdiation of Cr VI contaminiated soils and this paper considered tolerance to Cr VI.
The fact that the micro-organisms survive the Cr VI and then thrive in the Cr III enriched media demonstrates toxicity to Cr III to be significanty lower than Cr VI.
It was also found that Pseudomonas aeruginosa reduced Cr (VI) into Cr (III) with the conversion efficiency of 94% after and extended 48h treatment. - Executive summary:
Chromium 3+ exists in natural soils and is well tolerated by micro-organisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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