Chromium trifluoride

Short-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Study period:

48 hours

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

As with all inorganic salts, the significance for toxicity or environmental assessment is the presence of specific ions that will form when in solution or when in biological systems.In the case of Cr III salts, the counter ion will have an effect on solubility and this is itself dependant on the type of media being used and in particular the pH of that media. It is generally accepted that in the case of metal salts, testing with salts that are soluble in the respective test media will ensure maximum exposure of the metal ions. This will include chlorides and nitrates as being more soluble and will indeed have relevance when dissolved in acid media, such as if ingested.Read-across to other chromium III salts is therefore considered valid as long as the exposure in the test system is greater than would be expected for the substance under review for registration.

Principles of method if other than guideline:

48 hour acute toxicity

GLP compliance:

not specified

Test organisms (species):

Daphnia magna

Test type:

not specified

Water media type:

freshwater

Hardness:

52 mg/l CaCO3

Details on test conditions:

Static

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

ca. 16.8 mg/L

Conc. based on:

element

Water hardness mg/l CaCO3	48 hr EC50 µg chromium/l
52	16800
99	27400
110	26300
195	51400
215	58700

Conclusions:

In an unpublished study reported in this review article, the acute toxicity of chromium nitrate to Daphnia magna at 5 water hardnesses was measured and the 48-hr EC50 ranged from 16.8 mg chromium/L in soft water to 57.8 mg chromium/L in hard water.
Using the lower software water result of 16.8 mg/l, it is estimated that CF3 will have an EC of about 35 mg/l.

Description of key information

In an unpublished study reported in this review article, the acute toxicity of chromium nitrate to Daphnia magna at 5 water hardnesses was measured and the 48-hr EC50 ranged from 16.8 mg chromium/L in soft water to 57.8 mg chromium/L in hard water.

Estimated EC50 ca 35 mg/l for CrF3 which is close to the toxicity of flouride ions.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Effect concentration:

35 mg/L