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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96-h LC50 for cesium potassium fluoroaluminate in Gobiocypris rarus was >120 mg/L based on nominal concentrations.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 120 mg/L
Additional information
One reliable study is available and was selected as key study. The GLP-compliant OECD 203 guideline study with Gobiocypris rarus was conducted as part of a new chemical substance notification in China. The study was conducted as semi-static limit test at a nominal concentration of 120 mg/L. The treatment group and the control group had one replicate, each containing 10 fish and the test duration was 96h. No mortality occurred in the control during the test and the dissolved oxygen concentration was greater than 60% of the air saturation value throughout the test. Hence, the test was considered to be valid. During the test, the measured concentration of aluminum (Al) analysed by ICP-MS, varied greater than 20% during the test. Since the test substance consists of four elements (Cs, K, Al and F), the measured concentrations of the test substance were not actually calculated by the measured concentrations of Aluminium analyzed by ICP-MS. In order to reflect the toxicity of the test substance, the results were expressed as the nominal concentrations.The 96h LC50 (based on the nominal concentrations) for cesium tetrafluoroaluminate was >120 mg/L.
A previous study (Bouwman, 2004a) performed by NOTOX BV according to OECD 203 has been disregarded because of deficiencies in the analytical method. The quantification of the test substance is based on the analysis of cesium which is present at 5.64% w/w in the test substance. The measured concentrations of the test substance were actually calculated by the measured concentrations of Cesium.
Part of the test solutions prepared for the range-finding test and the final test were used in the simultaneously performed acute daphnia toxicity test (NOTOX project 394717). Analyses of a sample taken at the start of the final daphnia test from the undiluted filtrate prepared at a loading rate of 100 mg/L showed a cesium concentration of 505 µg/L (8.9 mg/L test substance) while a cesium concentration of only 178 µg/L (3.1 mg/L test substance) was measured in the same solution at the start of the final fish test. In addition, this concentration was much lower than the concentration found in the range-finding test in which a cesium concentration of 889 µg/L (15.8 mg/L test substance) was measured in the undiluted filtrate that was prepared in the same way and at the same concentration. Overall, the concentrations of cesium in the test solutions are significantly lower than expected based on the percentage of cesium in the test substance. No explanation was given for this difference.
Since the analytical method used to quantify the test substance in the test solution is not considered sufficiently robust, the effect concentrations found in this study are disregarded for assessment. In addition, the test substance consists of four elements (Cs, K, Al and F) and the biological effects are expected to be mostly governed by the presence of fluoride and aluminium ions formed upon dissociation of the fluoroaluminate moieties. Therefore in order to reflect the toxicity of the test substance, it is not correct to express the results as the mean measured cesium concentrations.
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