Registration Dossier
Registration Dossier
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EC number: 454-190-9 | CAS number: 324763-51-1
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish:
With high probability acutely not harmful to fish.
The toxicity of the test substance to fish was determined in a limit test conducted according to EU Method C.1 (cited as Directive 92/69/EEC, C.1) using Dani rerio as test species. The test concentrations were 0 mg/L (control) and 100 mg/L. Based on measured test concentrations, the 96h LC50 was determined to be > 100 mg/L (not neutralized).
Short-term toxicity to aquatic invertebrates:
With high probability not acutely harmful to aquatic invertebrates.
The toxicity of the substance to aquatic invertebrates was investigated in a limit test conducted according to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test; Novartis, 2004); the test organism was Daphnia magna. Based on measured test concentrations the 48-h EC50 was determined to be >100 mg/L (not pH-adjusted).
Toxicity to aquatic algae and plants:
With high probability acutely not harmful to aquatic algae and cyanobacteria.
The toxicity of the substance to aquatic algae was investigated in a limit test conducted according to EU Method C.3 (cited as Directive 92/69/EEC, C.3; Novartis, 2004); the test organism was Desmodesmus subspicatus. Based on measured test concentrations the 72-h ErC50 was determined to be >100 mg/L (not pH-adjusted); the 72 -h NOErC was >=100 mg/L.
Toxicity to microorganisms:
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
The key study is a GLP compliant OECD Guideline 209 study resulting in a 30-min EC EC50 value of >1,000 mg/L using domestic activated sludge as inoculum (BASF AG, 2005; no analytical monitoring performed). In a further supporting GLP compliant OECD 209 study (also performed without analytical monitoring), a 3-h EC50 value of 13,000 mg/L was observed with activated sludge from a domestic STP as inoculum (CETA, 2004). The 30-min EC50 of >1,000 mg/L will be used for the assessment.
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