Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 202-691-6 | CAS number: 98-67-9
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin corrosion: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Remarks:
- raw data are not available for analysis
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Evaluation of the Corrositex Method for Determine the Corrosivity Potential of Surfactants, Surfactant-based Formulations, Chemicals, and Mixtures
- Author:
- Gordon et al.
- Year:
- 1 998
- Bibliographic source:
- Advances in Animal Alternatives for Safety and Efficacy Testing
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 435 (In Vitro Membrane Barrier Test Method for Skin Corrosion)
- Version / remarks:
- No information on the conduct of the test is given in the publication, however it is assumed that the test was conducted at least similar to guideline.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-hydroxybenzenesulphonic acid
- EC Number:
- 202-691-6
- EC Name:
- 4-hydroxybenzenesulphonic acid
- Cas Number:
- 98-67-9
- Molecular formula:
- C6H6O4S
- IUPAC Name:
- 4-hydroxybenzenesulfonic acid
Constituent 1
In vitro test system
- Test system:
- artificial membrane barrier model
Results and discussion
In vitro
Results
- Irritation / corrosion parameter:
- penetration time (in minutes)
- Value:
- > 3 - < 30
- Vehicle controls validity:
- not specified
- Negative controls validity:
- not specified
- Positive controls validity:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- Category 1B (corrosive) based on GHS criteria
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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