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EC number: 229-186-3 | CAS number: 6424-76-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- May 15, 2015 - July 17, 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: guideline study (EC A.6. and OECD 105)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Water solubility:
- < 1 other: mg (TOC) /L
- Temp.:
- 20 °C
- pH:
- 6
- Executive summary:
The water solubility cS of the test item was determined at a temperature of 20 °C according to OECD 105. As the test item is not soluble in aqueous or organic solvents, it was not possible to analytically quantify Vat Black 16. Hence, the dissolved total organic carbon content (TOC) was measured.
It was determined to be:: < 1 mg (TOC) / L.
Reference
Individual results
Preliminary visual estimation of the water solubility
Different amounts of the test item were stirred in 100 mL or 500 mL distilled water and the mixtures were visually checked for any undissolved parts.Table2 shows the results from the preliminary test.
Table2: Appearance of the test mixtures
Amount of test item in mg |
Total volume in mL |
Appearance of mixture |
|||
17.8 |
100 |
undissolved1) |
|||
10.6 |
500 |
undissolved1) |
|||
3.5 |
500 |
undissolved1) |
1): After adding the indicated amount of water, the solution was stirred for approx. 72 h.
The preliminary visual experiments showed that the solubility of the test item in water is below 7 mg/L (without correction for the purity). As the test item is insoluble in organic solvents it is impossible to coat the sea sand of the columns with the test item. For this reason, the column elution method is not applicable and the water solubility had to be determined by the flask method.
Results of the flask method
After the equilibration time, precipitate was observed in the flasks of the test item-treated samples.The water solubility was calculated from the measured and unrounded concentration values and not from the rounded values given in Table3.
Table3: Solubility of the test item in water- experiments
Experiment |
24 h experiment |
48 h experiment |
72 h experiment |
Blank experiment (72 h) |
Amount of test item (mg) |
8.1 |
8.5 |
9.3 |
-- |
Amount of distilled water (mL) |
200 |
200 |
200 |
200 |
Stirring time at 30 °C (h) |
24 |
48 |
72 |
72 |
pH at 23°C |
6.0 |
6.0 |
6.1 |
5.9 |
Measured TOC concentration |
< 1 |
< 1 |
< 1 |
< 1 |
The TOC concentration in the aqueous samples was determined to be < 1 mg/l TOC.
Description of key information
The water solubility of the test item was determined by the flask method according to the European Commission Regulations (EC) No. 440/2008 and No. 260/2014, A.6. Water solubility; flask method and according to the OECD test guideline, OECD 105 Water solubility.
Key value for chemical safety assessment
Additional information
The water solubility was found to be below the quantification limit of 1 mg/l TOC.
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