Registration Dossier
Registration Dossier
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EC number: 930-776-4 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The negative results obtained in the referenced studies are considered worst-case since the test material used in these studies (manganese chloride) is more readily available due to its much higher solubility compared to the registered substance (trimanganese tetraoxide).
Short description of key information:
A critical analysis of all available literature showed no genetic toxicity for the substance. This conclusion is confirmed also with three standard in-vitro tests (IUCLID sections 8.4.1, 8.4.2 and 8.4.3)
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
All in vitro genotoxicity tests conducted in accordance with REACH regulation were negative and an additional in vivo mouse micronucleus test supports this non-classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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