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EC number: 221-916-9 | CAS number: 3279-27-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
CERI Japan (2008) provided a measured BCF value for read across substance o-tert-butylphenol of 78 for the common carp.
Key value for chemical safety assessment
- BCF (aquatic species):
- 78 L/kg ww
Additional information
Reliable measured and modeled BCF data for o-tert-amylphenol and its structural analogues o-tert-butylphenol and o-sec-butylphenol are available and included in the dossier.
The Chemical Evaluation and Research Institute Japan (2008) conducted a reliable BCF study (Klimisch 2) according to the OECD 305 guideline. The common carp, Cyprinus carpio, were exposed to the structural analogue o-tert-butylphenol where the uptake, tissue distribution and elimination of the test substance in freshwater exposure was investigated. Fish were exposed to measured concentrations of the test substance at 20 ug/L and 2 ug/L in a flow-through system for 28 days. The time of plateau was 15 days and the BCF was based on steady state. The measured BCF for the 20 ug/L exposure was 62 and the BCF for the 2 ug/L exposure was 78.
The Chemical Inspection and Testing Institute (2000) also conducted a reliable (Klimisch 2) BCF study following the OECD 305 guideline on the read across substance o-sec-butylphenol. Two-year old common carp, Cyprinus carpio, were exposed to measured concentrations of 0.001 and 0.10 mg/L in a flow-through system for 28 days. Study results indicated that the BCF for fish was 16 for the 0.10 mg/L concentration and 27 for the 0.001 mg/L concentration.
These measured BCF values are supported by calculated BCF and BAF values for o-tert-amylphenol. BCF values were calculated using the BCFBAF v3.01 module embedded within the EPISuite v4.11 computer model. The calculated BCF (regression-based model) was 121 L/kg wet-wt., while the BAF (Arnot-Gobas upper trophic) was 253 L/kg wet-wt.
Reliable measured and modeled BCF data for o-tert-amylphenol and its structural analogues o-tert-butylphenol and o-sec-butylphenol are available and included in the dossier. Chemical Evaluation and Research Institute Japan (2008) provide a measured BCF value of 78 for the common carp exposed to the read across substance o-tert-butylphenol. Consequently, this value will be taken for the aquatic bioaccumulation in aquatic organisms endpoint.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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